Reinert, L. S., Lopušná, K.
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, Vægter, C., Nyengaard, J. R., Fitzgerald, K. A.
& Paludan, S. R. (2016).
Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.
Nature Communications,
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Glerup, S., Bolcho, U., Bøggild, S., Vaegter, C. B., Smith, A. H., Nieto-Gonzalez, J. L., Ovesen, P. L., Pedersen, L. F., Fjorback, A. N., Kjolby, M., Login, H., Holm, M. M., Andersen, O. M., Nyengaard, J. R., Willnow, T. E.
, Jensen, K., Nykjaer, A. & Jensen, S. M. (2016).
SorCS2 is required for BDNF-dependent plasticity in the hippocampus.
Molecular Psychiatry,
21(12), 1740-1751.
https://doi.org/10.1038/mp.2016.108
Svenningsen, A. L. S., Jager, S. B., Richner, M., Dieu, R.
, Pallesen, L. T. & Vægter, C. B. (2016).
Sortilin in microglia reactivity: Investigating the mechanism underlying the impairment of neuropathic pain in sortilin knockout mice. Abstract from 10th FENS Forum of Neuroscience, København, Denmark.
Gonçalves, N. P., Vægter, C. B., Andersen, H., Østergaard, L., Calcutt, N. A.
& Jensen, T. S. (2017).
Schwann cell interactions with axons and microvessels in diabetic neuropathy.
Nature Reviews. Neurology,
13(3), 135-147.
https://doi.org/10.1038/nrneurol.2016.201
Svenningsen, A. L. S., Jager, S. B., Richner, M., Dieu, R.
, Pallesen, L. T. & Vægter, C. B. (2017).
Sortilin in microglia reactivity. Abstract from PhD Day 2017, Aarhus, Denmark.
Blechingberg, J., Poulsen, A. S. A.
, Kjølby, M., Monti, G., Allen, M.
, Ivarsen, A. K., Lincoln, S. J., Thotakura, G.
, Vægter, C. B., Ertekin-Taner, N.
, Nykjær, A. & Andersen, O. M. (2018).
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor.
Neurobiology of Aging,
71, 266.e11-266.e24.
https://doi.org/10.1016/j.neurobiolaging.2018.06.021
Richner, M., Ferreira, N., Dudele, A., Jensen, T. S., Vaegter, C. B. & Gonçalves, N. P. (2019).
Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy.
Frontiers in Neuroscience,
12, Article 1038.
https://doi.org/10.3389/fnins.2018.01038
Asad, J., Richner, M., Vægter, C. B., Nyengaard, J. R. & Jensen, P. H. (2019).
Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9.
Neuroscience Insights,
14(November-December), 1-12.
https://doi.org/10.1177/1179069519889022
Gonçalves, N. P., Mohseni, S., El Soury, M.
, Ulrichsen, M., Richner, M., Xiao, J., Wood, R. J.
, Andersen, O. M., Coulson, E. J., Raimondo, S., Murray, S. S.
& Vægter, C. B. (2019).
Peripheral Nerve Regeneration Is Independent From Schwann Cell p75NTR Expression.
Frontiers in Cellular Neuroscience,
13, Article 235.
https://doi.org/10.3389/fncel.2019.00235
Jager, S. E., Denk, F.
, Richner, M., Pallesen, L. T., McMahon, S. B.
& Vægter, C. B. (2019).
Satellite glial cells in neuropathic pain: An RNAseq study. Poster session presented at XIV European Meeting on Glial Cells in Health and Disease, Porto, Portugal.
Goncalves, N. P., Mohseni, S.
, Richner, M., Murray, S. S.
, Staehelin-Jensen, T. & Vægter, C. B. (2019).
Schwann cell p75 neurotrophic receptor modulates phagolysosomal pathways underlying diabetes induced neurodegeneration. Poster session presented at XIV European Meeting on Glial Cells in Health and Disease, Porto, Portugal.
Vægter, C. B., Staehelin-Jensen, T., Arendt-Nielsen, L.
& Finnerup, N. B. (2019).
Smertefysiologi 1: smerteanatomi og smertemekanismer. In M. U. Werner, N. B. Finnerup & L. Arendt-Nielsen (Eds.),
Smerter - baggrund, evidens og behandling (4 ed., pp. 36-51). FADL's Forlag.
Richner, M., Pallesen, L. T., Ulrichsen, M., Poulsen, E. T., Holm, T. H., Login, H., Castonguay, A., Lorenzo, L.-E.
, Gonçalves, N. P., Andersen, O. M., Lykke-Hartmann, K., Enghild, J. J., Rønn, L. C. B., Malik, I. J., De Koninck, Y., Bjerrum, O. J.
, Vægter, C. B. & Nykjær, A. (2019).
Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain.
Science Advances,
5(6), Article eaav9946.
https://doi.org/10.1126/sciadv.aav9946
Hammer, R. E., Richner, M., Vægter, C. B., Karlsson, P. & Nyengaard, J. R. (2019).
The effect of Recombinant Botulinum Neurotoxin A on neuropathic pain in Spared Nerve Injury mouse model. Poster session presented at 11th Congress of the European Pain Federation EFIC, Valencia, Spain.
Christensen, N. R., De Luca, M., Lever, M. B.
, Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T. ... Madsen, K. L. (2020).
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
EMBO Molecular Medicine,
12(6), Article 11248.
https://doi.org/10.15252/emmm.201911248
Jager, S. E., Pallesen, L. T., Richner, M., Harley, P., Hore, Z., McMahon, S., Denk, F.
& Vaegter, C. B. (2020).
Changes in the transcriptional fingerprint of satellite glial cells following peripheral nerve injury.
Glia,
68(7), 1375-1395.
https://doi.org/10.1002/glia.23785
Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Article 450.
https://doi.org/10.3390/biomedicines8110450
Gonçalves, N. P., Jager, S. E., Richner, M., Murray, S. S., Mohseni, S.
, Jensen, T. S. & Vaegter, C. B. (2020).
Schwann cell p75 neurotrophin receptor modulates small fiber degeneration in diabetic neuropathy.
Glia,
68(12), 2725-2743.
https://doi.org/10.1002/glia.23881
Kjolby, M., Pedersen, K. M., Breining, P., Wellner, N., Sørensen, K. M. J., Vittrup, D. M., Gjesing, A. M. P.
, Januliene, D., Manavalan, A., Rotman, M., Thotakura, G., Skeldal, S., Madsen, P.
, Thirup, S., Hermey, G.
, Vaegter, C. B., Möller, A., Asplund, O., Prasad, R. B.
... Nykjaer, A. (2020).
SorCS1 binds the insulin receptor to enhance insulin sensitivity. bioRxiv.
https://doi.org/10.1101/2020.11.10.376178
Monti, G., Jensen, M. L., Mehmedbasic, A., Jørgensen, M. M., Holm, I. E., Barkholt, P., Zole, E., Vægter, C. B., Vorum, H., Nyengaard, J. R. & Andersen, O. M. (2020).
SORLA Expression in Synaptic Plexiform Layers of Mouse Retina.
Molecular Neurobiology,
57(7), 3106-3117.
https://doi.org/10.1007/s12035-020-01946-x
Monti, G., Kjolby, M., Jensen, A. M. G., Allen, M., Reiche, J.
, Møller, P. L., Comaposada-Baró, R., Zolkowski, B. E., Vieira, C., Jørgensen, M. M., Holm, I. E., Valdmanis, P. N.
, Wellner, N., Vægter, C. B., Lincoln, S. J.
, Nykjær, A., Ertekin-Taner, N., Young, J. E.
, Nyegaard, M. & Andersen, O. M. (2021).
Expression of an alternatively spliced variant of SORL1 in neuronal dendrites is decreased in patients with Alzheimer's disease.
Acta Neuropathologica Communications,
9(1), Article 43.
https://doi.org/10.1186/s40478-021-01140-7
Ferreira, N., Richner, M., van der Laan, A.
, Bergholdt Jul Christiansen, I., Vægter, C. B., Nyengaard, J. R., Halliday, G. M., Weiss, J., Giasson, B. I., Mackenzie, I. R.
, Jensen, P. H. & Jan, A. (2021).
Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy.
Brain Communications,
3(2), Article fcab104.
https://doi.org/10.1093/braincomms/fcab104
Jan, A., Gonçalves, N. P., Vaegter, C. B., Jensen, P. H. & Ferreira, N. (2021).
The Prion-Like Spreading of Alpha-Synuclein in Parkinson's Disease: Update on Models and Hypotheses.
International Journal of Molecular Sciences ,
22(15), Article 8338.
https://doi.org/10.3390/ijms22158338
Ferreira, N., Gonçalves, N. P., Jan, A., Jensen, N. M., van der Laan, A., Mohseni, S.
, Vægter, C. B. & Jensen, P. H. (2021).
Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain.
Acta Neuropathologica Communications,
9(1), Article 31.
https://doi.org/10.1186/s40478-021-01131-8
Delaidelli, A.
, Richner, M., Jiang, L., van der Laan, A., Bergholdt Jul Christiansen, I., Ferreira, N., Nyengaard, J. R., Vægter, C. B., Jensen, P. H., Mackenzie, I. R., Sorensen, P. H.
& Jan, A. (2021).
α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.
Acta Neuropathologica Communications,
9(1), Article 105.
https://doi.org/10.1186/s40478-021-01209-3
Jager, S. E.
, Pallesen, L. T., Lin, L., Izzi, F.
, Pinheiro, A. M., Villa-Hernandez, S., Cesare, P.
, Vaegter, C. B. & Denk, F. (2022).
Comparative transcriptional analysis of satellite glial cell injury response.
Wellcome Open Research,
7, Article 156.
https://doi.org/10.12688/wellcomeopenres.17885.1
Ferreira, N., Richner, M., van der Laan, A., Jul Christiansen, I. B., Vægter, C. B., Nyengaard, J. R., Halliday, G. M., Weis, J., Giasson, B. I., Mackenzie, I. R.
, Jensen, P. H. & Jan, A. (2022).
Correction to: Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy.
Brain Communications,
4(2), fcac067. Article fcac067.
https://doi.org/10.1093/braincomms/fcac067
Richner, M., Gonçalves, N. P., Jensen, P. H., Nyengaard, J. R., Vægter, C. B. & Jan, A. (2022).
Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion.
STAR Protocols,
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https://doi.org/10.1016/j.xpro.2022.101181
Ulrichsen, M., Gonçalves, N. P., Mohseni, S., Hjæresen, S., Lisle, T. L.
, Molgaard, S., Madsen, N. K., Andersen, O. M., Svenningsen, Å. F.
, Glerup, S., Nykjær, A. & Vægter, C. B. (2022).
Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury.
Frontiers in Cellular Neuroscience,
16, Article 856734.
https://doi.org/10.3389/fncel.2022.856734
Jensen, A. M. G., Kitago, Y.
, Fazeli, E., Vægter, C. B., Small, S. A., Petsko, G. A.
& Andersen, O. M. (2023).
Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer.
Proceedings of the National Academy of Sciences (PNAS),
120(4), Article e2212180120.
https://doi.org/10.1073/pnas.2212180120
Lautrup, S., Myrup Holst, C., Yde, A., Asmussen, S., Thinggaard, V., Larsen, K., Laursen, L. S., Richner, M., Vaegter, C. B., Prieto, G. A., Berchtold, N., Cotman, C. W.
& Stevnsner, T. (2023).
The role of aging and brain-derived neurotrophic factor signaling in expression of base excision repair genes in the human brain.
Aging Cell,
22(9), Article e13905.
https://doi.org/10.1111/acel.13905
Jensen, B. N., Tong, T., Skovborg, G.
, Zhang, Y., Müller, C. A., Matthiesen, C. L., Eschen, J. T., Elbæk, K. J., Wang, Y., Pallesen, L. T., Seliktar, D.
, Dong, M., Vægter, C. B., Korshoej, A. R. & Chen, M. (2024).
Electromagnetic Stimulated Anisotropic Hydrogels for Guided Neuronal Morphogenesis. bioRxiv.
https://doi.org/10.1101/2024.09.29.615659
Theologidis, V., Ferreira, S. A., Jensen, N. M., Gomes Moreira, D., Ahlgreen, O. A., Hansen, M. W., Rosenberg, E. D., Richner, M., Faress, I., Gram, H., Jensen, P. H., Borghammer, P., Nyengaard, J. R., Romero-Ramos, M., Vægter, C. B., van de Berg, W. D. J.
, Van Den Berge, N. & Jan, A. (2025).
Bradykinesia and postural instability in a model of prodromal synucleinopathy with α-synuclein aggregation initiated in the gigantocellular nuclei.
Acta Neuropathologica Communications,
13(1), 32. Article 32.
https://doi.org/10.1186/s40478-025-01948-7
Omoniyi, A. A., Hammer, R. E., Josefsen, S.
, Richner, M., Lezmi, S.
, Vægter, C. B., Kalinichev, M.
, Karlsson, P. & Nyengaard, J. R. (2025).
The Activities of Recombinant Botulinum Toxin A on Spared Nerve Injury-Induced Neuropathic Pain in a Diabetic Mice Model.
Toxins,
17(11), Article 545.
https://doi.org/10.3390/toxins17110545
E. Hammer, R., A. Omoniyi, A., Richner, M., Lezmi, S.
, B. Vaegter, C., Kalinichev, M.
, Karlsson, P. & R. Nyengaard, J. (2025).
The effect of recombinant botulinum neurotoxin A on neuropathic pain in the spared nerve injury mouse model.
Journal of Neural Transmission,
132, 1779–1795.
https://doi.org/10.1007/s00702-025-02978-0
Kaas, M., Dinesen, S. B., Ahlgreen, O., Madsen, P., Mølgaard, S., Dalby, A.
, Gustafsen, C., Olsen, D., Duan, J., Vilstrup, J., Lende, J., Nordestgaard, S., Zayats, T., Knappskog, P. M., Johansson, S., Neckelmann, G., Franke, B.
, Thirup, S., Børglum, A. ... Skeldal, S. (2026).
A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity.
Molecular Psychiatry,
31(3), 1311-1324.
https://doi.org/10.1038/s41380-025-03242-3
Ahlgreen, O. A., Hansen, M. W., Baake, J., Hybel, T. E., Rossi, R., Lai, X., Sankaranarayanan, I.
, Pold, J. A., Lin, L., Reinert, L., Paludan, S. R., Price, T. J.
, Pallesen, L. T. & Vægter, C. B. (2026).
Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion.
Advanced Science,
13(1), Article e11569.
https://doi.org/10.1002/advs.202511569
Pallesen, L. T., Pedersen, A.-K., Sankaranarayanan, I., Feldman-Goriachnik, R.
, Ahlgreen, O. A., Pinheiro, A. M., He, L.
, Baake, J., Hansen, M. W., Richner, M., Ellegaard, L. D., Petersen, K. A., Fjord-Larsen, L., Olsen, J. V., Munro, G., Hanani, M., Price, T. J.
& Vægter, C. B. (2026).
Meteorin Resolves Nociceptive Hypersensitivity by Reducing Connexin-Mediated Coupling in Satellite Glial Cells.
Glia,
74(2), Article e70105.
https://doi.org/10.1002/glia.70105
de Waal, M. W. J., van der Lee, S. J.
, Lunding, M., Boonkamp, L., Barrett, N.
, Monti, G., Jensen, A. M. G., Vaegter, C. B., Raska, J., Cesnarikova, S., Sedmik, J., Trieu, C., Weiss, M. M., van Spaendonk, R., Vermunt, L., Ozhegov, G., Tesi, N., Hulsman, M., Januliene, D. ... Holstege, H. (2026).
Soluble SORL1 in cerebrospinal fluid as a marker for functional impact of rare SORL1 variants.
Alzheimer's & Dementia,
22(2), Article e71042.
https://doi.org/10.1002/alz.71042