Klinger, S. C., Højland, A., Jain, S.
, Kjolby, M., Madsen, P., Svendsen, A. D., Olivecrona, G., Bonifacino, J. S.
& Nielsen, M. S. (2016).
Polarized Trafficking of the Sorting Receptor SorLA in Neurons and MDCK Cells.
FEBS journal,
283(13), 2476–2493.
https://doi.org/10.1111/febs.13758
Kjærgaard, M., Skeldal, S., Raarup, M. K., Nykjær, A., Nyengaard, J. R. & Nielsen, M. S. (2008).
Using FRET in the study of the Vps10pD receptors: Annual Meeting of the Nordic Microscopy Society (Scandem).
Kahns, S., Lykkebo, S., Jakobsen, L. D.
, Nielsen, M. S. & Jensen, P. H. (2002).
Caspase-mediated parkin cleavage in apoptotic cell death.
Journal of Biological Chemistry,
277, 15303-15308.
Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B.
, Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T. (2017).
Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma.
Scientific Reports,
7(1), 10396. Article 10396.
https://doi.org/10.1038/s41598-017-11220-1
Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S.
, Nielsen, M. S., Moos, T. & Andresen, T. L. (2018).
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.
Theranostics,
8(12), 3416-3436.
https://doi.org/10.7150/thno.25228
Jensen, P. H., Islam, K., Kenney, J.
, Nielsen, M. S., Power, J. & Gai, W. P. (2000).
Microtubule-associated protein 1B is a component of cortical lewy bodies.
Journal of Biological Chemistry,
275, 21500-21507.
Jensen, P. H., Hager, H.
, Nielsen, M. S., Højrup, P.
, Gliemann, J. & Jakes, R. (1999).
Alpha-synuclein binds TAU and stimulates the protein kinase A-catalyzed TAU phosphorylation of serine residues 261 and 356.
Journal of Biological Chemistry,
274, 25481-25489.
Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, C. G. & Goedert, M. (1998).
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
J Biol Chem Commun,
273, 26292-26294.
Jensen, P. H., Højrup, P., Hager, H.
, Nielsen, M. S., Jacobsen, L., Olesen, O. F.
, Gliemann, J. & Jakes, R. (1997).
Binding of Aβ to α- and β-synucleins: Identification of segments in α-synuclein/NAC precursor that bind Aβ and NAC.
Biochem. J.,
323, 539-546.
Jacobsen, L.
, Madsen, P., Jacobsen, C., Nielsen, M. S., Gliemann, J. & Petersen, C. M. (2001).
Activation and functional characterization of the mosaic receptor SorLA/LR11.
Journal of Biological Chemistry,
276, 22788-22796.
Jacobsen, L.
, Madsen, P. S., Nielsen, M. S., Geraerts, W. P. M.
, Gliemann, J., Smit, A. B.
& Pedersen, J. C. M. (2002).
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding.
FEBS Letters,
511(1-3), 155-158.
Hudecz, D., Khire, T., Chung, H. L., Adumeau, L., Glavin, D., Luke, E.
, Nielsen, M. S., Dawson, K. A., McGrath, J. L. & Yan, Y. (2020).
Ultrathin Silicon Membranes for in Situ Optical Analysis of Nanoparticle Translocation across a Human Blood-Brain Barrier Model.
ACS Nano,
14(1), 1111-1122.
https://doi.org/10.1021/acsnano.9b08870
Hudecz, D., Sigurdardóttir, S. B.
, Christensen, S. C., Hempel, C., Urquhart, A. J., Andresen, T. L.
& Nielsen, M. S. (2021).
Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells.
PLOS ONE,
16(4 ), Article e0249686.
https://doi.org/10.1371/journal.pone.0249686
Hudecz, D., McCloskey, M. C., Vergo, S., Christensen, S., McGrath, J. L.
& Nielsen, M. S. (2023).
Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device.
International Journal of Molecular Sciences ,
24(6), Article 5624.
https://doi.org/10.3390/ijms24065624
Horn, I. R.
, Moestrup, S. K., van den Berg, B. M. M., Pannekoek, H.
, Nielsen, M. S. & van Zonneveld, A. J. (1995).
Analysis of the binding of pro-urokinase-plasminogen activator inhibitor-1 complex to the low density lipoprotein receptor-related protein using a Fab fragment selected from a phage-displayed Fab library.
Journal of Biological Chemistry,
270, 11770-11775.
Holst, M. R., de Wit, N. M., Ozgür, B., Brachner, A., Hyldig, K., Appelt-Menzel, A., Sleven, H., Cader, Z., de Vries, H. E., Neuhaus, W., Jensen, A., Brodin, B.
& Nielsen, M. S. (2023).
Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier.
Fluids and Barriers of the CNS,
20(1), Article 82.
https://doi.org/10.1186/s12987-023-00480-x
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, J.
, Glerup, S. & Nielsen, M. S. (2018).
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner.
Behavioural Brain Research,
348, 90-100.
https://doi.org/10.1016/j.bbr.2018.04.017
Hersom, M., Helms, H. C., Pretzer, N., Goldeman, C., Jensen, A. I., Severin, G.
, Nielsen, M. S., Holm, R. & Brodin, B. (2016).
Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers.
Molecular and Cellular Neuroscience,
76, 59-67.
https://doi.org/10.1016/j.mcn.2016.08.009
Hager, H.
, Jensen, P. H., Hamilton-Dutoit, S. J., Nielsen, M. S., Birckbichler, P.
& Gliemann, J. (1997).
Expression of tissue transglutaminase in human bladder carcinoma.
J Pathol,
183, 398-403.
Gustafsen, C., Nielsen, M. S., Madsen, P. S., Dennes, A., Schu, P.
& Petersen, C. M. (2006).
The APP binding receptor SorLA mediates Golgi-endosome shuttling. Poster session presented at EMBO research conference on Interface of Cell Biology and Cellular Microbiology. Macromolecular Complexes in Microbial Pathogenesis, Membrane Trafficking and Cell Signalling, San Feliu de Guixols, Spain.
Gottfredsen, R. H., Tran, S. M.-H.
, Larsen, U. G., Madsen, P., Nielsen, M. S., Enghild, J. J. & Petersen, S. V. (2012).
The C-terminal proteolytic processing of extracellular superoxide dismutase is redox regulated.
Free Radical Biology & Medicine,
52(1), 191-197.
https://doi.org/10.1016/j.freeradbiomed.2011.10.443
Gliemann, J., Nykjær, A., Petersen, C. M., Jørgensen, K. E.
, Nielsen, M. S., Andreasen, P., Christensen, E. I., Lookene, A., Olivecrona, G.
& Moestrup, S. K. (1994).
The α2-macroglobulin receptor/low density lipoprotein receptor-related protein. Binding and endocytosis of fluid-phase and membrane-associated ligands.
New York Academy of Sciences. Annals,
737, 20-38.
Dennes, A.
, Madsen, P. S., Nielsen, M. S., Pedersen, J. C. M. & Pohlmann, R. (2002).
The Yeast Vps10p Cytoplasmic Tail Mediates Lysosomal Sorting in Mammalian Cells and Interacts with Human GGAs.
Journal of Biological Chemistry,
277(14), 12288-12293.
Christensen, S. C., Krogh, B. O., Jensen, A.
, Andersen, C. B. F., Christensen, S.
& Nielsen, M. S. (2020).
Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain.
Scientific Reports,
10(1), Article 14582.
https://doi.org/10.1038/s41598-020-71286-2
Christensen, B., Toth, A. E., Nielsen, S. S. E., Scavenius, C., Petersen, S. V., Enghild, J. J., Rasmussen, J. T., Nielsen, M. S. & Sørensen, E. S. (2020).
Transport of a peptide from bovine αs1-casein across models of the intestinal and blood–brain barriers.
Nutrients,
12(10), Article 3157.
https://doi.org/10.3390/nu12103157
Christensen, S. C., Hudecz, D., Jensen, A., Christensen, S.
& Nielsen, M. S. (2021).
Basigin Antibodies with Capacity for Drug Delivery Across Brain Endothelial Cells.
Molecular Neurobiology,
58(9), 4392-4403.
https://doi.org/10.1007/s12035-021-02421-x
Chan, W. L., Shaw, P. C., Tam, S. C.
, Jacobsen, C., Gliemann, J. & Nielsen, M. S. (2000).
Trichosanthin interacts with and enters cells via LDL receptor family members.
Biochem. Biophys. Res. Commun.,
270, 453-457.
Celis, J., Rasmussen, H. H., Olsen, E.
, Madsen, P. S., Leffers, H.
, Honore, B., Dejgaard, K., Gromov, P., Hoffmann, H. J.
, Nielsen, M. S., Vassilev, A., Vintermyr, O., Hao, J., Celis, A.
, Basse, B., Lauridsen, J. B., Ratz, G. P., Andersen, A. H.
, Walbum, E. ... Vandekerckhove, J. (1993).
The human keratinocyte two-dimentional gel protein database: Update 1993.
Electrophoresis,
14, 1091-1198.
Celis, J., Rasmussen, H. H.
, Madsen, P. S., Leffers, H.
, Honore, B., Dejgaard, K., Gesser, B., Olsen, E., Gromov, P., Hoffmann, H. J.
, Nielsen, M. S., Celis, A.
, Lauridsen, J. B., Basse, B., Ratz, G. P., Andersen, A. H.
, Walbum, E., Nielsen, I. K., Nielsen, H. ... Vandekerckhove, J. (1992).
The human keratinocyte two-dimensional gel protein database: Update 1992: Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases.
Electrophoresis,
13, 893-959.
Carlo, A.-S.
, Gustafsen, C., Mastrobuoni, G.
, Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M.
, Nykjaer, A., Herz, J., Heeren, J., Kempa, S.
, Petersen, C. M. & Willnow, T. E. (2013).
The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain.
Journal of Neuroscience,
33(1), 358-70.
https://doi.org/10.1523/JNEUROSCI.2425-12.2013
Burkhart, A., Skjørringe, T., Johnsen, K. B.
, Siupka, P., Thomsen, L. B.
, Nielsen, M. S., Thomsen, L. L. & Moos, T. (2015).
Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier.
Molecular Neurobiology.
https://doi.org/10.1007/s12035-015-9582-7