Nielsen, K. M.
, Jørgensen, N. P., Kyneb, M. H.
, Borghammer, P., Meyer, R. L., Thomsen, T. R.
... Alstrup, A. K. O. (2018).
Preclinical evaluation of potential infection-imaging probe [68Ga]Ga-DOTA-K-A9 in sterile and infectious inflammation.
Journal of Labelled Compounds and Radiopharmaceuticals,
61(10), 780-795.
https://doi.org/10.1002/jlcr.3640Jørgensen, N. P., Alstrup, A. K. O., Mortensen, F. V., Knudsen, K., Jakobsen, S., Madsen, L. B. ... Borghammer, P. (2017).
Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV.
European Journal of Nuclear Medicine and Molecular Imaging,
44(3), 449–458.
https://doi.org/10.1007/s00259-016-3555-6
Horsager, J., Lausten, S. B., Bender, D., Munk, O. L. & Keiding, S. (2017).
Hepatic metabolism of 11C-methionine and secretion of 11C-protein measured by PET in pigs.
American Journal of Nuclear Medicine and Molecular Imaging,
7(4), 167-173.
Nielsen, K. M.
, Bender, D., Nielsen, O. L., Jensen, S. B.
& Alstrup, A. K. O. (2017).
In vivo stability evaluation of 68Ga-labelled dodecapeptide for bacterial infection imaging. Poster session presented at 22nd International Symposium on Radiopharmaceutical Sciences, Dresden, Germany.
Marzano, C.
, Jakobsen, S., Salinas, C., Tang, S. P.
, Bender, D., Passchier, J. & Plisson, C. (2017).
Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system.
Journal of Labelled Compounds and Radiopharmaceuticals,
60(12), 556-565.
https://doi.org/10.1002/jlcr.3535Nielsen, K. M., Kyneb, M. H.
, Alstrup, A. K. O., Jensen, J. J.
, Bender, D., Schønheyder, H. C. ... Jensen, S. B. (2016).
(68)Ga-labeled phage-display selected peptides as tracers for positron emission tomography imaging of Staphylococcus aureus biofilm-associated infections: Selection, radiolabelling and preliminary biological evaluation.
Nuclear Medicine and Biology,
43(10), 593-605.
https://doi.org/10.1016/j.nucmedbio.2016.07.002Tentillier, N., Etzerodt, A., Olesen, M. N., Rizalar, F. S., Jacobsen, J., Bender, D. ... Romero-Ramos, M. (2016).
Anti-Inflammatory Modulation of Microglia via CD163-Targeted Glucocorticoids Protects Dopaminergic Neurons in the 6-OHDA Parkinson's Disease Model.
The Journal of neuroscience : the official journal of the Society for Neuroscience,
36(36), 9375-90.
https://doi.org/10.1523/JNEUROSCI.1636-16.2016
Afzelius, P.
, Nielsen, O. L., Alstrup, A. K. O., Bender, D., Leifsson, P. S., Jensen, S. B. & Schønheyder, HC. (2016).
Biodistribution of the radionuclides (18)F-FDG, (11)C-methionine, (11)C-PK11195, and (68)Ga-citrate in domestic juvenile female pigs and morphological and molecular imaging of the tracers in hematogenously disseminated Staphylococcus aureus lesions.
American Journal of Nuclear Medicine and Molecular Imaging,
6(1), 42-58.
Afzelius, P., Nielsen, O. L.
, Alstrup, A. K. O., Bender, D., Leifsson, P. S., Jensen, S. B. & Schønheyder, H. C. (2016).
Biodistribution of the radionuclides 18F-FDG, 11C-methionine, 11C-PK11195, and 68Ga-citrate in domestic juvenile female pigs and morphological and molecular imaging of the tracers in hematogenously disseminated Staphylococcus aureus lesions. Poster session presented at Dansk Radiologisk Selskabs 11. årsmøde med Dansk Selskab for Klinisk Fysiologi og Nuklearmedicin og Dansk Ultralyddiagnostisk Selskab, Odense, Denmark.
Nielsen, M. S., GLUD, AN., Møller, A., Mogensen, P., Bender, D., Sørensen, J. C.
... Bjarkam, C. R. (2016).
Continuous MPTP intoxication in the Göttingen minipig results in chronic parkinsonian deficits.
Acta Neurobiologiae Experimentalis,
76(3), 199-211.
Lou, H. O. C., Rosenstand, A.
, Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U. ... Møller, A. (2016).
Exogenous dopamine reduces GABA receptor availability in the human brain.
Brain and Behavior,
6(7), e00484.
https://doi.org/10.1002/brb3.484
Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T. ... Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.
Brain,
139(7), 2039-2049.
https://doi.org/10.1093/brain/aww098
Stokholm, M. G., Høyer, S., Borre, M., Bender, D., Jakobsen, S., Frøkiær, J. & Borghammer, P. (2016).
Molecular imaging of cholinergic processes in prostate cancer using (11)C-donepezil and (18)F-FEOBV.
European Journal of Nuclear Medicine and Molecular Imaging.
https://doi.org/10.1007/s00259-015-3143-1
Tvilling, L., Glud, A. N., Orlowski, D., Jakobsen, J.
, Pedersen, M., Ettrup, K. S. E. ... Sørensen, J. C. H. (2016).
The anatomy and neurohistology of the minipig pituitary. Poster session presented at Neuroscience 2016, San Diego, United States.
Afzelius, P.
, Alstrup, A. K. O., Schønheyder, H. C.
, Borghammer, P., Jensen, S. B.
, Bender, D. & Nielsen, O. L. (2016).
Utility of (11)C-methionine and (11)C-donepezil for imaging of Staphylococcus aureus induced osteomyelitis in a juvenile porcine model: comparison to autologous (111)In-labelled leukocytes, (99m) Tc-DPD, and (18)F-FDG.
American Journal of Nuclear Medicine and Molecular Imaging,
6(6), 286-300.
Dam, J. H.
, Bender, D., Peters, D. & Någren, K. (2016).
[¹¹C]NS9531, [¹¹C]NS9762 and [¹¹C]NS6417, specific SERT tracers: pre-clinical evaluation in pigs and optimization of synthesis conditions using [¹¹C]methyl triflate.
Nuclear Medicine and Biology,
43(1), 42-51.
https://doi.org/10.1016/j.nucmedbio.2015.10.004Eichendorff, S., Svendsen, P., Bender, D., Keiding, S., Christensen, E. I., Deleuran, B. & Moestrup, S. K. (2015).
Biodistribution and PET Imaging of a Novel [(68)Ga]-Anti-CD163-Antibody Conjugate in Rats with Collagen-Induced Arthritis and in Controls.
Molecular Imaging and Biology,
17(1), 87-93.
https://doi.org/10.1007/s11307-014-0768-6
Jødal, L., Hansen, S. B.
, Jensen, S. B., Bender, D., Alstrup, A. K. O., Afzelius, P. & Nielsen, O. L. (2015).
PET tracer uptake kinetics in inflammation and infection imaging using a porcine osteomyelitis model – preliminary results. Poster session presented at Dansk Selskab for Medicinsk Fysik, Nyborg, Denmark.
Vibholm, A. K., Landau, A. M., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Simonsen, M.
... Brooks, D. (2015).
Preclinical in-vivo imaging of activated NMDA receptor ion channels with the novel radioligand 18F-GE179. Abstract from Pd.d.-dag, Aarhus, Denmark.
Nielsen, O. L., Afzelius, P.
, Bender, D., Schønheyder, H. C., Leifsson, P. S., Nielsen, K. M.
... Alstrup, A. K. O. (2014).
Comparison of autologous 111In-leukocytes, 18F-FDG, 11C-methionine, 11C-PK11195 and 68Ga-citrate for diagnostic nuclear imaging in a juvenile porcine haematogenous Staphylococcus aureus osteomyelitis model. Abstract from SPECT and PET imaging in porcine inflammation and infection models, København, Denmark.
Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O. ... Borghammer, P. (2014).
In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses.
Journal of Nuclear Medicine,
55(11), 1818-24.
https://doi.org/10.2967/jnumed.114.143859
Winterdahl, M., Audrain, H., Landau, A. M., Smith, D. F., Bonaventure, P., Shoblock, J. R.
... Bender, D. (2014).
PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs.
Journal of Nuclear Medicine,
55(4), 635-9.
https://doi.org/10.2967/jnumed.113.125351
Glerup, S., Olsen, D., Vægter, C. B., Gustafsen, C., Sjøgaard, S., Hermey, G. ... Nykjær, A. (2014).
SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia.
Neuron,
82(5), 1074–1087.
https://doi.org/10.1016/j.neuron.2014.04.022
Vase, K. H., Peters, D., Nielsen, E. Ø.
, Alstrup, A. K. O. & Bender, D. (2014).
[11C]NS8880, a promising PET radiotracer targeting the norepinephrine transporter.
Nuclear Medicine and Biology,
41, 758-764.
https://doi.org/10.1016/j.nucmedbio.2014.06.004
Afzelis, P., Jensen, S. B.
, Alstrup, A. K. O., Larsen, J. O., Schønheyder, H. C., Nielsen, K. M.
... Bender, D. (2013).
Grise-osteomyelitis-model: hvilke sporstoffer?. Abstract from Dansk Selskab for Klinisk Fysiologi og Nuklearmedicin, Korsør, Denmark.
Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C.
... Kringelbach, M. L. (2013).
PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.
Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A.
... Kringelbach, M. L. (2013).
PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Glerup, S., Lume, M.
, Olsen, D., Nyengaard, J. R., Vaegter, C. B., Gustafsen, C. ... Petersen, C. M. (2013).
SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET.
Cell Reports,
3, 186-199.
https://doi.org/10.1016/j.celrep.2012.12.011
Marthi, K.
, Hansen, S. B., Jakobsen, S., Bender, D., Smith, S. B.
& Smith, D. F. (2012).
Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors.
Applied Radiation and Isotopes,
59(2-3), 175-9.
Smith, D., Stork, B.
, Wegener, G., Ashkanian, M., Jakobsen, S., Bender, D. ... Rosenberg, R. (2009).
[(11)C]Mirtazapine binding in depressed antidepressant nonresponders studied by PET neuroimaging.
Psychopharmacology,
206, 133-140.
https://doi.org/10.1007/s00213-009-1587-3
Vase, K., Peters, D., Nielsen, E. Ø.
, Alstrup, A. K. O. & Bender, D. (2009).
[11C]NS8880 a New Ligand Targeting the Norepinephrine (NET) Transporter. Poster session presented at EANM '09, Barcelona, Spain.
Sørensen, M., Munk, O. L., Mortensen, F. V., Olsen, A. K., Bender, D., Bass, L.
& Keiding, S. (2008).
Hepatic uptake and metabolism of galactose can be quantified by in vivo 2-[18F] Fluoro-2-deoxy-galactose positron emission tomography. Abstract from Turku PET Symposium, Turku, Finland.
Sørensen, M., Munk, O. L., Mortensen, F. V., Olsen, A. K., Bender, D., Bass, L.
& Keiding, S. (2008).
Hepatic uptake and metabolism of galactose can be quantified in vivo by 2-[18F]Fluoro-2-deoxy-galactose Positron Emission Tomography. American Journal of Physiology: Gastrointestinal and Liver Physiology.
https://doi.org/10.1152/ajpgi.00004.2008
Smith, D., Hansen, S., Jakobsen, S., Bender, D., Audrain, H.
, Ashkanian, M. ... Rosenberg, R. (2008).
Neuroimaging of mirtazapine enantiomers in humans. Psychopharmacology,
200, 273-279.
https://doi.org/10.1007/s00213-008-1208-6
Bjarkam, C. R., Nielsen, M. S., GLUD, AN., Rosendal, F., Mogensen, P., Bender, D. ... Sørensen, J. C. (2008).
Neuromodulation in a minipig MPTP model of Parkinson disease.
British Journal of Neurosurgery,
22 Suppl 1, S9-12.
https://doi.org/10.1080/02688690802448285
Bjarkam, C., Nielsen, M. S., Glud, A. N., Rosendal, F., Mogensen, P., Bender, D. ... Sørensen, J. C. H. (2008).
Neuromodulation in a minipig MTTP model of Parkinson disease.
British Journal of Neurosurgery,
22/1, 9-12.
Smith, D. F., Hansen, S. B., Jakobsen, S., Bender, D., Audrain, H., Ashkanian, M. ... Rosenberg, R. (2008).
Regional binding potentials of [11C]mirtazapine enantiomers in human brain.
European Neuropsychopharmacology,
18(S4), S260-S261.
Bender, D., Peters, D.
, Olsen, A. K., Østergaard Nielsen, E., Redrobe, J. P., Vang Hansen, K.
& Gjedde, A. (2008).
Structure activity relationship for tree different selective serotonin reuptake inhibitors (SSRI�s): NS6417, NS9531 and NS9762.
NeuroImage, T88.
Sørensen, M., Mortensen, F. V., Bender, D., Olsen, A. K., Munk, O. L., Keiding, S. & Bass, L. (2007).
Dynamic 18F-deoxy-2-galactose PET can measure regional liver function in pigs.
Journal of Nuclear Medicine, 177P.
Bender, D., Audrain, H., Olsen, A. K., Jensen, M. S.
, West, M. J. & Gjedde, A. (2007).
Is aging a reason for the failure of 11C-Pittsburgh Compound B in transgenic mice model. Abstract from 17th International Symposium on Radiopharmaceutical Science, Aachen, Germany.
Smith, D. F., Stork, B. S., Wegener, G., Jakobsen, S., Bender, D., Audrain, H. ... Rosenberg, R. (2007).
Receptor occupancy of mirtazapine determined by PET in healthy volunteers.
Psychopharmacology,
195(1), 131-138.
https://doi.org/10.1007/s00213-007-0877-x
Smith, D. F., Stork, B. S.
, Wegener, G., Jakobsen, S., Bender, D., Audrain, H. ... Rosenberg, R. (2007).
Receptor occupancy of mirtazapine determined by PET in healty volunteers.
Psychopharmacology.
Keiding, S., Sørensen, M., Bender, D., Munk, O. L., Ott, P. & Vilstrup, H. (2006).
Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by PET.
Hepatology,
43, 42-50.
Iversen, P., Hansen, D. A.
, Bender, D., Rodell, A., Munk, O. L., Cumming, P. & Keiding, S. (2006).
Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy.
Eur. J. Nucl. Med. Mol. Imaging, (33), 810-816.
