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Strom, N. I., Verhulst, B., Bacanu, S. A., Cheesman, R., Purves, K. L., Gedik, H., Mitchell, B. L., Kwong, A. S., Faucon, A. B., Singh, K., Medland, S., Colodro-Conde, L., Krebs, K., Hoffmann, P., Herms, S., Gehlen, J., Ripke, S., Awasthi, S., Palviainen, T. ... 23andMe Research Team (2026). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nature Genetics, 58. https://doi.org/10.1038/s41588-025-02485-8
Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Attention-Deficit/Hyperactivity Disorder (ADHD) Working Group of the Psychiatric Genomics Consortium, Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nicotine Dependence GenOmics (iNDiGO) Consortium, Brikell, I., Grove, J., Sonuga-Barke, E., Hübel, C., Larsen, J. T. & Petersen, L. V. (2026). Mapping the genetic landscape across 14 psychiatric disorders. Nature, 649(8096), 406-415. https://doi.org/10.1038/s41586-025-09820-3
Goleva, S. B., Leu, C., Anne Feng, Y. C., Burstein, D., Venkatesh, S., Birnbaum, R., Rajagopal, V. M., Straub, P., Christensen, J., Bautista, J. F., Busch, R. M., Najm, I. M., Grove, J., Børglum, A. D., Voloudakis, G., Roussos, P., Smoller, J., Lal, D. & Davis, L. K. (2026). Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients. Biological Psychiatry Global Open Science, 6(1), Article 100604. https://doi.org/10.1016/j.bpsgos.2025.100604
Kweon, H., Burik, C. A. P., Ning, Y., Ahlskog, R., Xia, C., Abner, E., Bao, Y., Bhatta, L., Faquih, T. O., de Feijter, M., Fisher, P., Gelemanović, A., Giannelis, A., Hottenga, J.-J., Khalili, B., Lee, Y., Li-Gao, R., Masso, J., Myhre, R. ... Rosendaal, F. R. (2025). Associations between common genetic variants and income provide insights about the socio-economic health gradient. Nature Human Behaviour, 9(4), 794-805. Article 12681. https://doi.org/10.1038/s41562-024-02080-7
Horsdal, H. T., Albiñana, C., Zhu, Z., Boelt, S. G., Borbye-Lorenzen, N., Cohen, A. S., Skogstrand, K., Melgaard, L., MacSween, N. J., Thorbek, M. J., Plana-Ripoll, O., Petersen, L. V., Bulik, C. M., Børglum, A. D., Mors, O., Nordentoft, M., Werge, T., Moen, G.-H., D'Urso, S. ... McGrath, J. J. (2025). Convergent evidence linking neonatal vitamin D status and risk of neurodevelopmental disorders: a Danish case-cohort study. The Lancet Psychiatry, 12(6), 410-420. https://doi.org/10.1016/S2215-0366(25)00099-9
Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, Article e0243639. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.0828
Rietkerk, J., Krebs, M. D., Mefford, J., Huang, L., Hellberg, K.-L. G., Børglum, A., Werge, T., Kendler, K. S., Flint, J., Schork, A. J., Dahl, A., Cai, N. & iPSYCH Study Consortium (2025). Genetic risk effects on psychiatric disorders act in sets. medRxiv. https://doi.org/10.1101/2025.07.23.25332043
Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. ... 23andMe Inc (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57(6), 1389-1401. Article 230. https://doi.org/10.1038/s41588-025-02189-z
Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Als, T. D., Nissen, J. B., Meier, S. M., Mattheisen, M., PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025
Akter, H., Rahaman, M. A., Eshaque, T. B., Mohamed, N., Islam, A., Morshed, M., Shahin, Z., Muhaimin, A., Foyzullah, A. M., Mim, R. A., Omar, F. B., Hasan, M. N., Satsangi, D., Ahmed, N., Al Saba, A., Jahan, N., Hossen, M. A., Mondol, M. A., Sakib, A. S. ... Uddin, M. (2025). Genomic insights from a deeply phenotyped highly consanguineous neurodevelopmental disorders cohort. Genetics in Medicine, 27(1), Article 101282. https://doi.org/10.1016/j.gim.2024.101282
Borbye-Lorenzen, N., Holmgaard, S., Ottosson, F., Nudel, R., Appadurai, V., Laursen, T. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T., Benros, M. E., Hougaard, D. M. & Skogstrand, K. (2025). High level of immunoglobulin G targeting mycoplasma or cytomegalovirus in the newborn increases risk of ADHD. Brain, Behavior, and Immunity, 123, 99-107. https://doi.org/10.1016/j.bbi.2024.09.009
Voloudakis, G., Therrien, K., Tomasi, S., Rajagopal, V. M., Choi, S. W., Demontis, D., Fullard, J. F., Børglum, A. D., O’Reilly, P. F., Hoffman, G. E. & Roussos, P. (2025). Neuropsychiatric polygenic scores are weak predictors of professional categories. Nature Human Behaviour, 9(3), 595-608. Article 2457. https://doi.org/10.1038/s41562-024-02074-5
Zhang, X., Grove, J., Gu, Y., Buus, C. K., Nielsen, L. K., Neufeld, S. A. S., Koko, M., Malawsky, D. S., Wade, E. M., Verhoef, E., Gui, A., Hegemann, L., Geschwind, D. H., Wray, N. R., Havdahl, A., Ronald, A., St Pourcain, B., Robinson, E. B., Bourgeron, T. ... APEX consortium (2025). Polygenic and developmental profiles of autism differ by age at diagnosis. Nature, 646(8087), 1146-1155. https://doi.org/10.1038/s41586-025-09542-6
Demontis, D., Duan, J., Hsu, Y.-H. H., Pintacuda, G., Grove, J., Nielsen, T. T., Thirstrup, J., Martorana, M., Botts, T., Satterstrom, F. K., Bybjerg-Grauholm, J., Tsai, J. H. Y., Glerup, S., Hoogman, M., Buitelaar, J., Klein, M., Ziegler, G. C., Jacob, C., Grimm, O. ... Børglum, A. D. (2025). Rare genetic variants confer a high risk of ADHD and implicate neuronal biology. Nature. Advance online publication. https://doi.org/10.1038/s41586-025-09702-8
Montalbano, S., Krebs, M. D., Rosengren, A., Vaez, M., Hellberg, K. L. G., Mortensen, P. B., Børglum, A. D., Geschwind, D. H., Raznahan, A., Thompson, W. K., Helenius, D., Werge, T., Ingason, A. & iPSYCH Investigators (2024). Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology. npj Genomic Medicine, 9(1), Article 67. https://doi.org/10.1038/s41525-024-00450-8
Bergstedt, J., Pasman, J. A., Ma, Z., Harder, A., Yao, S., Parker, N., Treur, J. L., Smit, D. J. A., Frei, O., Shadrin, A. A., Meijsen, J. J., Shen, Q., Hägg, S., Tornvall, P., Buil, A., Werge, T., Hjerling-Leffler, J., Als, T. D., Børglum, A. D. ... Fang, F. (2024). Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature Cardiovascular Research, 3(6), 754-769. https://doi.org/10.1038/s44161-024-00488-y
Vaez, M., Montalbano, S., Waples, R., Krebs, M. D., Hellberg, K.-L. G., Gådin, J., Bybjerg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Nordentoft, M., Geschwind, D. H., Helenius, D., Werge, T., Schork, A. J. & Ingason, A. (2024). Evaluating the Joint Effects of Recurrent Copy Number Variants and Polygenic Scores on the Risk of Psychiatric Disorders in the iPSYCH2015 Case-Cohort Sample. https://doi.org/10.1101/2024.09.23.24314234
Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babić, D., Bacanu, S.-A., Baker, D. G. ... AURORA Study (2024). Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nature Genetics, 56(5), 792-808. https://doi.org/10.1038/s41588-024-01707-9
iPSYCH Consortium (2024). Phenotypic and ancestry-related assortative mating in autism. Molecular Autism, 15(1), 27. Article 27. https://doi.org/10.1186/s13229-024-00605-5
LaBianca, S., Brikell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C. E., Walker, R., Gådin, J. R., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Pedersen, M. G., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Kendler, K. S. ... Schork, A. J. (2024). Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder. Nature Genetics, 56(2), 234-244. https://doi.org/10.1038/s41588-023-01593-7
Vaez, M., Montalbano, S., Calle Sánchez, X., Georgii Hellberg, K.-L., Dehkordi, S. R., Krebs, M. D., Meijsen, J., Shorter, J., Bybjerg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Helenius, D., Raznahan, A., Thompson, W. K. ... iPSYCH Investigators (2024). Population-Based Risk of Psychiatric Disorders Associated With Recurrent Copy Number Variants. JAMA Psychiatry, 81(10), 957-966. Article 10. https://doi.org/10.1001/jamapsychiatry.2024.1453
Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group, Børglum, A., Mors, O. & Mortensen, P. B. (2024). Potential causal association between gut microbiome and posttraumatic stress disorder. Translational Psychiatry, 14, Article 67. https://doi.org/10.1038/s41398-024-02765-7
Patel, K. H. S., Walters, G. B., Stefánsson, H., Stefánsson, K., Degenhardt, F., Nothen, M., Van Der Veen, T., Demontis, D., Borglum, A., Kristiansen, M., Bass, N. J. & McQuillin, A. (2024). Predicting ADHD in alcohol dependence using polygenic risk scores for ADHD. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 195(4), Article e32967. https://doi.org/10.1002/ajmg.b.32967
Pisanu, C., Congiu, D., Meloni, A., Paribello, P., Severino, G., Ardau, R., Chillotti, C., Als, T. D., Børglum, A. D., Del Zompo, M., Manchia, M. & Squassina, A. (2024). Sex differences in shared genetic determinants between severe mental disorders and metabolic traits. Psychiatry Research, 342, Article 116195. https://doi.org/10.1016/j.psychres.2024.116195
Nielsen, T. T., Duan, J., Levey, D. F., Walters, G. B., Johnson, E. C., Thorgeirsson, T., Werge, T., Mortensen, P. B., Stefansson, H., Stefansson, K., Hougaard, D. M., Agrawal, A., Gelernter, J., Grove, J., Børglum, A. & Demontis, D. (2024). Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD. Nature Mental Health, 2(9), 1071-1083. Article 108535. https://doi.org/10.1038/s44220-024-00277-3
Daskalakis, N. P., Iatrou, A., Chatzinakos, C., Jajoo, A., Snijders, C., Wylie, D., DiPietro, C. P., Tsatsani, I., Chen, C.-Y., Pernia, C. D., Soliva-Estruch, M., Arasappan, D., Bharadwaj, R. A., Collado-Torres, L., Wuchty, S., Alvarez, V. E., Dammer, E. B., Deep-Soboslay, A., Duong, D. M. ... PTSD Working Group of Psychiatric Genomics Consortium** (2024). Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science, 384(6698), Article eadh3707. https://doi.org/10.1126/science.adh3707
Kim, S. W., Lee, H., Song, D. Y., Lee, G. H., Ji, J., Park, J. W., Han, J. H., Lee, J. W., Byun, H. J., Son, J. H., Kim, Y. R., Lee, Y., Kim, J., Jung, A., Lee, J., Kim, E., Kim, S. H., Lee, J. H., Satterstrom, F. K. ... An, J. Y. (2024). Whole genome sequencing analysis identifies sex differences of familial pattern contributing to phenotypic diversity in autism. Genome Medicine, 16(1), Article 114. https://doi.org/10.1186/s13073-024-01385-6
Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Mortensen, P. B., Delaneau, O., Werge, T. & Schork, A. J. (2023). Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks. Communications Biology, 6(1), Article 101. https://doi.org/10.1038/s42003-023-04477-y
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, T. & Ingason, A. (2023). Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study. The Lancet Psychiatry, 10(2), 129-138. https://doi.org/10.1016/S2215-0366(23)00004-4
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G. ... Børglum, A. D. (2023). Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. Nature Medicine, 29(7), 1832-1844. https://doi.org/10.1038/s41591-023-02352-1
Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babic, D., Bacanu, S.-A. ... Koenen, K. C. (2023). Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. medRxiv. https://doi.org/10.1101/2023.08.31.23294915
Ribasés, M., Mitjans, M., Hartman, C. A., Soler Artigas, M., Demontis, D., Larsson, H., Ramos-Quiroga, J. A., Kuntsi, J., Faraone, S. V., Børglum, A. D., Reif, A., Franke, B. & Cormand, B. (2023). Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes. Neuroscience and Biobehavioral Reviews, 153, Article 105313. https://doi.org/10.1016/j.neubiorev.2023.105313
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B. ... McGrath, J. J. (2023). Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots. Nature Communications, 14(1), Article 852. https://doi.org/10.1038/s41467-023-36392-5