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Nielsen, T. T., Duan, J., Levey, D. F., Walters, G. B., Johnson, E. C., Thorgeirsson, T., Werge, T., Mortensen, P. B., Stefansson, H., Stefansson, K., Hougaard, D. M., Agrawal, A., Gelernter, J., Grove, J., Børglum, A. & Demontis, D. (2024). Shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD. Nature Mental Health, 2(9), 1071-1083. Article 108535. https://doi.org/10.1038/s44220-024-00277-3
Daskalakis, N. P., Iatrou, A., Chatzinakos, C., Jajoo, A., Snijders, C., Wylie, D., DiPietro, C. P., Tsatsani, I., Chen, C.-Y., Pernia, C. D., Soliva-Estruch, M., Arasappan, D., Bharadwaj, R. A., Collado-Torres, L., Wuchty, S., Alvarez, V. E., Dammer, E. B., Deep-Soboslay, A., Duong, D. M. ... PTSD Working Group of Psychiatric Genomics Consortium** (2024). Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science, 384(6698), Article eadh3707. https://doi.org/10.1126/science.adh3707
Kim, S. W., Lee, H., Song, D. Y., Lee, G. H., Ji, J., Park, J. W., Han, J. H., Lee, J. W., Byun, H. J., Son, J. H., Kim, Y. R., Lee, Y., Kim, J., Jung, A., Lee, J., Kim, E., Kim, S. H., Lee, J. H., Satterstrom, F. K. ... An, J. Y. (2024). Whole genome sequencing analysis identifies sex differences of familial pattern contributing to phenotypic diversity in autism. Genome Medicine, 16(1), Article 114. https://doi.org/10.1186/s13073-024-01385-6
Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Mortensen, P. B., Delaneau, O., Werge, T. & Schork, A. J. (2023). Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks. Communications Biology, 6(1), Article 101. https://doi.org/10.1038/s42003-023-04477-y
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, T. & Ingason, A. (2023). Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study. The Lancet Psychiatry, 10(2), 129-138. https://doi.org/10.1016/S2215-0366(23)00004-4
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G. ... Børglum, A. D. (2023). Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. Nature Medicine, 29(7), 1832-1844. https://doi.org/10.1038/s41591-023-02352-1
Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babic, D., Bacanu, S.-A. ... Koenen, K. C. (2023). Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. medRxiv. https://doi.org/10.1101/2023.08.31.23294915
Ribasés, M., Mitjans, M., Hartman, C. A., Soler Artigas, M., Demontis, D., Larsson, H., Ramos-Quiroga, J. A., Kuntsi, J., Faraone, S. V., Børglum, A. D., Reif, A., Franke, B. & Cormand, B. (2023). Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes. Neuroscience and Biobehavioral Reviews, 153, Article 105313. https://doi.org/10.1016/j.neubiorev.2023.105313
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B. ... McGrath, J. J. (2023). Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots. Nature Communications, 14(1), Article 852. https://doi.org/10.1038/s41467-023-36392-5
Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H. ... ADHD Working Group of the Psychiatric Genomics Consortium (2023). Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. Nature Genetics, 55(2), 198-208. https://doi.org/10.1038/s41588-022-01285-8
Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G., Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T. ... Demontis, D. (2023). Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity. Scientific Reports, 13, Article 429. https://doi.org/10.1038/s41598-022-26845-0
Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J. E., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., Andreassen, O. A. ... Ruderfer, D. M. (2023). GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. American Journal of Psychiatry, 180(10), 723-738. https://doi.org/10.1176/appi.ajp.21121266
Levey, D. F., Galimberti, M., Deak, J. D., Wendt, F. R., Bhattacharya, A., Koller, D., Harrington, K. M., Quaden, R., Johnson, E. C., Gupta, P., Biradar, M., Lam, M., Cooke, M., Rajagopal, V. M., Empke, S. L. L., Zhou, H., Nunez, Y. Z., Kranzler, H. R., Edenberg, H. J. ... Veterans Affairs Million Veteran Program (2023). Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications. Nature Genetics, 55(12), 2094-2103. https://doi.org/10.1038/s41588-023-01563-z
Zhou, H., Kember, R. L., Deak, J. D., Xu, H., Toikumo, S., Yuan, K., Lind, P. A., Farajzadeh, L., Wang, L., Hatoum, A. S., Johnson, J., Lee, H., Mallard, T. T., Xu, J., Johnston, K. J. A., Johnson, E. C., Nielsen, T. T., Galimberti, M., Dao, C. ... Million Veteran Program (2023). Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. Nature Medicine, 29(12), 3184-3192. https://doi.org/10.1038/s41591-023-02653-5
Rolland, T., Cliquet, F., Anney, R. J. L., Moreau, C., Traut, N., Mathieu, A., Huguet, G., Duan, J., Warrier, V., Portalier, S., Dry, L., Leblond, C. S., Douard, E., Amsellem, F., Malesys, S., Maruani, A., Toro, R., Børglum, A. D., Grove, J. ... Bourgeron, T. (2023). Phenotypic effects of genetic variants associated with autism. Nature Medicine, 29(7), 1671-1680. https://doi.org/10.1038/s41591-023-02408-2
Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2023). Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study. Psychological Medicine, 53(1), 217-226. https://doi.org/10.1017/S0033291721001410
Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2023). Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability. American Journal of Human Genetics, 110(7), 1207-1215. https://doi.org/10.1016/j.ajhg.2023.06.006
Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Werge, T. M., Melbye, M., Hougaard, D. M., Larsen, L. A., Christensen, S. T. & Christiansen, M. (2023). The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement. Brain Communications, 5(1), Article fcad004. https://doi.org/10.1093/braincomms/fcad004
Cabana-Domínguez, J., Llonga, N., Arribas, L., Alemany, S., Vilar-Ribó, L., Demontis, D., Fadeuilhe, C., Corrales, M., Richarte, V., Børglum, A. D., Ramos-Quiroga, J. A., Soler Artigas, M. & Ribasés, M. (2023). Transcriptomic risk scores for attention deficit/hyperactivity disorder. Molecular Psychiatry, 28(8), 3493-3502. https://doi.org/10.1038/s41380-023-02200-1
Hsu, Y. H. H., Pintacuda, G., Liu, R., Nacu, E., Kim, A., Tsafou, K., Petrossian, N., Crotty, W., Suh, J. M., Riseman, J., Martin, J. M., Biagini, J. C., Mena, D., Ching, J. K. T., Malolepsza, E., Li, T., Singh, T., Ge, T., Egri, S. B. ... Wellcome Trust Case Control Consortium (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience, 26(5), Article 106701. https://doi.org/10.1016/j.isci.2023.106701
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S.-H., Ferreira, T., Highland, H. H. ... Understanding Society Scientific Group (2022). A saturated map of common genetic variants associated with human height. Nature, 610(7933), 704–712. https://doi.org/10.1038/s41586-022-05275-y
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, M., Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, T. (2022). Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders. Archives of General Psychiatry, 79(1), 59-69. https://doi.org/10.1001/jamapsychiatry.2021.3392
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, M., Børglum, A. D., Hougaard, D. M., Werge, T., Rasmussen, S. & Benros, M. E. (2022). Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression. Science Advances, 8(26), eabi7293. Article eabi7293. https://doi.org/10.1126/sciadv.abi7293
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B. ... Demontis, D. (2022). Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder. Nature Genetics, 54(8), 1117-1124. https://doi.org/10.1038/s41588-022-01143-7
Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E. ... Nievergelt, C. M. (2022). Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biological Psychiatry, 91(7), 626-636. https://doi.org/10.1016/j.biopsych.2021.09.020
Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Børglum, A. D., Werge, T., Nordentoft, M., Mortensen, P. B. & Agerbo, E. (2022). Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism. Autism Research, 15(1), 171-182. https://doi.org/10.1002/aur.2629
Grotzinger, A. D., Mallard, T. T., Akingbuwa, W. A., Ip, H. F., Adams, M. J., Lewis, C. M., McIntosh, A. M., Grove, J., Dalsgaard, S., Lesch, K. P., Strom, N., Meier, S. M., Mattheisen, M., Børglum, A. D., Mors, O., Breen, G., iPSYCH, Tourette Syndrome and Obsessive Compulsive Disorder Working Group of the Psychiatric Genetics Consortium, Bipolar Disorder Working Group of the Psychiatric Genetics Consortium ... Nivard, M. G. (2022). Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. Nature Genetics, 54(5), 548-559. https://doi.org/10.1038/s41588-022-01057-4
Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Rowitch, D. H., Hurles, M. E., Geschwind, D. H., Børglum, A. D., Robinson, E. B., Grove, J., Martin, H. C., Bourgeron, T., Baron-Cohen, S., EU-AIMS LEAP ... Spectrum 10K and APEX Consortia (2022). Genetic correlates of phenotypic heterogeneity in autism. Nature Genetics, 54(9), 1293-1304. https://doi.org/10.1038/s41588-022-01072-5
Eising, E., Mirza-Schreiber, N., de Zeeuw, E. L., Wang, C. A., Truong, D. T., Allegrini, A. G., Shapland, C. Y., Zhu, G., Wigg, K. G., Gerritse, M. L., Molz, B., Alagoz, G., Gialluisi, A., Abbondanza, F., Rimfeld, K., van Donkelaar, M., Liao, Z., Jansen, P. R., Andlauer, T. F. M. ... Fisher, S. E. (2022). Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people. Proceedings of the National Academy of Sciences (PNAS), 119(35), Article e2202764119. https://doi.org/10.1073/pnas.2202764119
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022). Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes. Brain : a journal of neurology, 145(2), 555–568. https://doi.org/10.1093/brain/awab260
Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M. ... Musliner, K. L. (2022). Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample. Biological Psychiatry: Global Open Science, 2(4), 400-410. https://doi.org/10.1016/j.bpsgos.2021.11.003
Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O. ... Bønnelykke, K. (2022). Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB. Journal of Allergy and Clinical Immunology, 150(3), 622-630. https://doi.org/10.1016/j.jaci.2022.03.019
GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry: Global Open Science, 2(2), 115-126. https://doi.org/10.1016/j.bpsgos.2021.07.008
Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J. ... Indonesia Schizophrenia Consortium (2022). Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature, 604(7906), 502-508. https://doi.org/10.1038/s41586-022-04434-5