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, Mors, O., McQuillin, A.
, Børglum, A. D. & Nyegaard, M. (2016).
CACNA1C hypermethylation is associated with bipolar disorder.
Translational Psychiatry,
6(6), e831. Article e831.
https://doi.org/10.1038/tp.2016.99
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes.
Genetics (Print),
203(4), 1901-1913.
https://doi.org/10.1534/genetics.116.189498
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 5th International Conference on Quantitative Genetics , Madison, United States.
https://doi.org/10.1534/genetics.116.189498
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 2nd Annual Danish Bioinformatics Conference, Odense, Denmark.
https://doi.org/10.1534/genetics.116.189498
Nissen, J. B., Søholm Hansen, C.
, Starnawska, A., Mattheisen, M., Børglum, A., Buttenschøn, H. N. & Hollegård, M. (2016).
DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD.
Frontiers in Psychiatry,
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https://doi.org/10.3389/fpsyt.2016.00035
Viuff, A.-C. F., Pedersen, L. H., Kyng, K. J., Staunstrup, N. H., Børglum, A. & Henriksen, T. B. (2016).
Epigenetic changes in newborns exposed to antidepressant medication during pregnancy - a planned genome wide study. Poster session presented at 2016 Epidemiology Conference of the Americas, Miami, United States.
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B.
, Grove, J., Maller, J., Samocha, K. E., Sanders, S. J., Ripke, S., Martin, J.
, Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D.
, Mortensen, P. B., Børglum, A. D. ... Als, T. D. (2016).
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
Nature Genetics,
48(5), 552–555.
https://doi.org/10.1038/ng.3529Staunstrup, N. H., Starnawska, A., Nyegaard, M., Christiansen, L.
, Nielsen, A. L., Børglum, A. & Mors, O. (2016).
Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.
Clinical Epigenetics (Print),
8(81), Article 81.
https://doi.org/10.1186/s13148-016-0242-1
Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J.
, Wang, J., Nordentoft, M., Werge, T. M.
, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J.
& Hollegaard, M. V. (2016).
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.
PLoS One,
11(4), e0153253. Article e0153253.
https://doi.org/10.1371/journal.pone.0153253
Starnawska, A., Demontis, D., McQuillin, A., O'Brien, N. L.
, Staunstrup, N. H., Mors, O., Nielsen, A. L., Børglum, A. D. & Nyegaard, M. (2016).
Hypomethylation of FAM63B in bipolar disorder patients.
Clinical Epigenetics (Print),
8(52), 1-6. Article 52.
https://doi.org/10.1186/s13148-016-0221-6
Fryland, T., Christensen, J. H., Pallesen, J., Mattheisen, M., Palmfeldt, J., Bak, M.
, Grove, J., Demontis, D., Blechingberg, J., Ooi, H. S., Nyegaard, M., Hauberg, M. E., Tommerup, N.
, Gregersen, N., Mors, O., Corydon, T. J., Nielsen, A. L. & Børglum, A. D. (2016).
Identification of the BRD1 interaction network and its impact on mental disorder risk.
Genome Medicine,
8(1), 53.
https://doi.org/10.1186/s13073-016-0308-x
Benros, M. E.
, Trabjerg, B. B., Meier, S., Mattheisen, M., Mortensen, P. B., Mors, O., Børglum, A. D., Hougaard, D. M., Nørgaard-Pedersen, B., Nordentoft, M.
& Agerbo, E. (2016).
Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia.
Biological Psychiatry,
80(8), 609–616.
https://doi.org/10.1016/j.biopsych.2016.04.008Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G.
, Borglum, A., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W.
, Mattheisen, M., Morris, D., Mowry, B., Müller-Mhysok, B. ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016).
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study.
PLoS Genetics,
12(10), e1006343. Article e1006343.
https://doi.org/10.1371/journal.pgen.1006343Hauberg, M. E., Holm-Nielsen, M. H., Mattheisen, M., Askou, A. L., Grove, J., Børglum, A. D. & Corydon, T. J. (2016).
Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
26(9), 1522-1526.
https://doi.org/10.1016/j.euroneuro.2016.06.014
Gregersen, N., Lescai, F., Liang, J., Li, Q.
, Als, T. D., Buttenschøn, H. N., Hedemand, A., Biskopstø, M., Wang, J., Wang, A.
, Børglum, A., Mors, O. & Demontis, D. (2016).
Whole-exome sequencing implicates DGKH as a risk gene for panic disorder in the Faroese population.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
171(8), 1013-1022.
https://doi.org/10.1002/ajmg.b.32464
Demontis, D., Lescai, F., Børglum, A., Glerup, S., Østergaard, S. D., Mors, O., Li, Q., Liang, J., Jiang, H., Li, Y., Wang, J., Lesch, K.-P., Reif, A., Buitelaar, J. K. & Franke, B. (2016).
Whole-Exome Sequencing Reveals Increased Burden of Rare Functional and Disruptive Variants in Candidate Risk Genes in Individuals With Persistent Attention-Deficit/Hyperactivity Disorder.
Journal of the American Academy of Child and Adolescent Psychiatry,
55(6), 521-523.
https://doi.org/10.1016/j.jaac.2016.03.009
Björkman, A.
, Qvist, P., Du, L., Bartish, M., Zaravinos, A., Georgiou, K.
, Børglum, A., Gatti, R. A., Törngren, T. & Pan-Hammerström, Q. (2015).
Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells.
Proceedings of the National Academy of Sciences (PNAS),
112(7), 2157-2162.
https://doi.org/10.1073/pnas.1418947112Rajkumar, A. P., Christensen, J. H., Mattheisen, M., Jacobsen, I., Bache, I.
, Pallesen, J., Grove, J., Qvist, P., Mcquillin, A., Gurling, H. M., Tümer, Z.
, Mors, O. & Børglum, A. D. (2015).
Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.
Bipolar Disorders (English Edition, Online),
17(2), 205-211.
https://doi.org/10.1111/bdi.12239
Nyegaard, M., Rendtorff, N. D.
, Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., Hedemand, A., Buniello, A., Niola, F., Overgaard, M. T., Leal, S. M., Ahmad, W.
, Wikman, F. P., Petersen, K. B., Crüger, D. G., Oostrik, J., Kremer, H., Tommerup, N., Frödin, M.
... Børglum, A. D. (2015).
A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.
PLoS Genetics,
11(7), e1005386.
https://doi.org/10.1371/journal.pgen.1005386
Loh, P.-R., Bhatia, G., Gusev, A., Finucane, H. K., Bulik-Sullivan, B. K., Pollack, S. J., Schizophrenia Working Group of the Psychiatric Genomics Consortium (Anders Børglum, Jakob Grove; members of -), O’Donovan, M. C., Neale, B. M., Patterson, N. & Price, A. L. (2015).
Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis.
Nature Genetics,
47, 1385–1392.
https://doi.org/10.1038/ng.3431Liu, S., Huang, S., Rao, J., Ye, W., Genome Denmark Consortium (Anders Børglum, member of -), Krogh, A.
& Wang, J. (2015).
Discovery, genotyping and characterization of structural variation and novel sequence at single nucleotide resolution from de novo genome assemblies on a population scale.
GigaScience,
4, 64.
https://doi.org/10.1186/s13742-015-0103-4Starnawska, A., McQuillin, A.
, Demontis, D., Pen, A., Hedemand, A., Johannesen, M. D., Lescai, F., Als, T. D., Grove, J., Staunstrup, N. H., Nielsen, A. L., Jarram, A., O'Brian, N.
, Mors, O., Børglum, A. & Nyegaard, M. (2015).
DNA methylation of CACNA1C in bipolar disorder. Poster session presented at ESHG 2015, Glasgow, United Kingdom.
Bak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyegaard, M., Nyengaard, J. R., Børglum, A., Mors, O., Dorph-Petersen, K.-A. & Nielsen, A. L. (2015).
Evaluating the Usability of Long-Term Stored Human Brain Bank Tissue for the Analysis of Epigenetic Markers. Poster session presented at Psykiatriens 10. forskningsdag, Risskov, Denmark.
Luo, Y., Blechingberg, J., Fernandes, A. M., Li, S., Fryland, T., Børglum, A. D., Bolund, L. & Nielsen, A. L. (2015).
EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions.
BMC Genomics,
16(1), Article 929.
https://doi.org/10.1186/s12864-015-2125-9
Rajkumar, A. P.
, Qvist, P., Lazarus, R.
, Lescai, F., Ju, J.
, Nyegaard, M., Mors, O., Børglum, A. D., Li, Q.
& Christensen, J. H. (2015).
Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq.
BMC Genomics,
16, 548.
https://doi.org/10.1186/s12864-015-1767-yRohde, P. D., Demontis, D., Arvidson, S. M. N., Madsen, L. S., Loeschcke, V.
, Sørensen, P., Børglum, A. & Kristensen, T. N. (2015).
Functional Insight From Fruit Flies on Human ADHD Candidate Genes. In
Genes, Brain, and Behavior 2015: 17th Annual Meeting of the International Behavioural and Neural Genetics Society (pp. 35).
Eickhardt, E. A., Als, T. D., Mattheisen, M., Hauberg, M. E., Grove, J., Børglum, A. & Lescai, F. (2015).
Genome-Wide Landscape of Genetic Variation with a Functional Impact on Predicted Binding Activity of Transcription Factor Binding Sites. Poster session presented at ESHG 2015, Glasgow, United Kingdom.
Meier, S. M., Agerbo, E., Maier, R.
, Pedersen, C. B., Lang, M.
, Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T.
, Mors, O., Hougaard, D. M., Børglum, A. D. ... MooDS SCZ Consortium (2015).
High loading of polygenic risk in cases with chronic schizophrenia.
Molecular Psychiatry, 1-6.
https://doi.org/10.1038/mp.2015.130
Als, T. D., Lescai, F., Dahl, H.
, Demontis, D., Wang, A., Andorsdottir, G., Biskopstø, M., Johansen, O.
, Grove, J., Nyegaard, M., Bolund, L., Mors, O., Jun, W.
& Børglum, A. (2015).
Identifying Rare Variation in Cases of Schizophrenia in the Isolated Population of the Faroe Islands using Whole-genome Sequencing. Poster session presented at XXIII World Congress of Psychiatric Genetics, Toronto, Canada.
Buttenschøn, H. N., Demontis, D., Ollendorff, M. K., Elfving, B., Jensen, S. M., Gustafsen, C., Kærlev, L.
, Petersen, C. M., Børglum, A., Mors, O. & Pedersen, S. G. (2015).
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF.
Translational Psychiatry,
5(e677).
https://doi.org/10.1038/tp.2015.167
Debost, J.-C., Petersen, L., Grove, J., Khashan, A.
, Henriksen, T., Mors, O., Hollegaard, M., Hougaard, D.
, Nyegaard, M., Børglum, A. & Mortensen, P. B. (2015).
Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia.
Psychoneuroendocrinology,
60, 18-27.
https://doi.org/10.1016/j.psyneuen.2015.05.013
Bulik-Sullivan, B. K., Loh, P.-R., Finucane, H. K., Ripke, S.
, Yang, J., Patterson, N., Daly, M. J., Price, A. L., Neale, B. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Anders Børglum and Ole Mors, members of -) (2015).
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nature Genetics,
47(3), 291–295.
https://doi.org/10.1038/ng.3211Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., Hayeck, T., Won, H.-H., Kathiresan, S., Pato, M., Pato, C., Tamimi, R., Stahl, E., Zaitlen, N., Pasaniuc, B.
... Børglum, A. (2015).
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
American Journal of Human Genetics,
97(4), 576-92.
https://doi.org/10.1016/j.ajhg.2015.09.001
Besenbacher, S., Liu, S., Izarzugaza, J. M. G.
, Grove, J., Belling, K., Bork-Jensen, J., Huang, S.
, Als, T. D., Li, S., Yadav, R., Rubio-García, A.
, Lescai, F., Demontis, D., Rao, J., Ye, W.
, Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R. ... Rasmussen, S. (2015).
Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios.
Nature Communications,
6, Article 5969.
https://doi.org/10.1038/ncomms6969
Bolund, L., Brunak, S., Brünner, N.
, Børglum, A., Pedersen, O. B., Danielsen, I., Flindt, E. N., Hansen, T., Jespersen, J., Kristiansen, K., Olesen, P., Sørensen, T.
& Ørntoft, T. F. (2015).
Paradigmeskifte i dansk sundhedsvidenskab: Nye muligheder i diagnostik og behandling.
Videnskab.dk.
Agerbo, E., Sullivan, P. F.
, Vilhjálmsson, B. J., Pedersen, C. B., Mors, O., Børglum, A. D., Hougaard, D. M.
, Hollegaard, M. V., Meier, S., Mattheisen, M., Ripke, S., Wray, N. R.
& Mortensen, P. B. (2015).
Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.
J A M A Psychiatry.
https://doi.org/10.1001/jamapsychiatry.2015.0346
Luo, X.-J.
, Mattheisen, M., Li, M., Huang, L., Rietschel, M.
, Børglum, A. D., Als, T. D., van den Oord, E. J., Aberg, K. A.
, Mors, O., Mortensen, P. B., Luo, Z., Degenhardt, F., Cichon, S., Schulze, T. G., Nöthen, M. M., Su, B., Zhao, Z., Gan, L. ... iPSYCH-GEMS SCZ working group (Jakob Grove, member) (2015).
Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function.
Schizophrenia Bulletin.
https://doi.org/10.1093/schbul/sbv017Gregersen, N. O., Buttenschøn, H. N., Hedemand, A., Dahl, H. A.
, Kristensen, A. S., Clementsen, B.
, Woldbye, D. P. D., Koefoed, P., Erhardt, A., Kruse, T. A., Wang, A. G.
, Børglum, A. D. & Mors, O. (2014).
Are TMEM genes potential candidate genes for panic disorder? Psychiatric Genetics,
24(1), 37-41.
https://doi.org/10.1097/YPG.0000000000000022
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J.
, Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I. ... GROUP (2014).
Common variant at 16p11.2 conferring risk of psychosis.
Molecular Psychiatry,
19(1), 108-114.
https://doi.org/10.1038/mp.2012.157Marcheco-Teruel, B., Parra, E. J., Fuentes-Smith, E., Salas, A.
, Buttenschøn, H. N., Demontis, D., Torres-Español, M., Marín-Padrón, L. C., Gómez-Cabezas, E. J., Alvarez-Iglesias, V., Mosquera-Miguel, A., Martínez-Fuentes, A., Carracedo, A.
, Børglum, A. D. & Mors, O. (2014).
Cuba: exploring the history of admixture and the genetic basis of pigmentation using autosomal and uniparental markers.
PLoS Genetics,
10(7), e1004488.
https://doi.org/10.1371/journal.pgen.1004488Elfving, B., Buttenschøn, H. N., Foldager, L., Poulsen, P. H. P.
, Grynderup, M. B., Hansen, A. M.
, Kolstad, H. A., Kaerlev, L., Mikkelsen, S.
, Børglum, A. D., Wegener, G. & Mors, O. (2014).
Depression and BMI influences the serum vascular endothelial growth factor level.
International Journal of Neuropsychopharmacology,
17(9), 1409-1417.
https://doi.org/10.1017/S1461145714000273
Børglum, A. D., Demontis, D., Grove, J., Pallesen, J., Hollegaard, M. V.
, Pedersen, C. B., Hedemand, A., Mattheisen, M., Uitterlinden, A.
, Nyegaard, M., Orntoft, T., Wiuf, C., Didriksen, M., Nordentoft, M., Nöthen, M. M., Rietschel, M., Ophoff, R. A., Cichon, S., Yolken, R. H. ... GROUP Investigators (2014).
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.
Molecular Psychiatry,
Mar;19(3), 325-33.
https://doi.org/10.1038/mp.2013.2
Schaldemose, E. L., Horjales-Araujo, E.
, Demontis, D., Børglum, A. D., Svensson, P. & Finnerup, N. B. (2014).
No association of polymorphisms in the serotonin transporter gene with thermal pain sensation in healthy individuals.
Molecular Pain,
10(1), 76.
https://doi.org/10.1186/1744-8069-10-76
Als, T. D., Lescai, F., Dahl, H. A.
, Grove, J., Demontis, D., Wang, A. G., Andorsdottir, G., Biskopstø, M., Johansen, O.
, Nyegaard, M., Bolund, L., Mors, O., Wang, J.
& Børglum, A. (2014).
Population Structure & Cryptic Relatedness of the isolated Population of the Faroe Islands. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Denmark.
Nicodemus, K. K., Hargreaves, A., Morris, D., Anney, R., Gill, M., Corvin, A., Donohoe, G. & Schizophrenia Psychiatric Genome-wide Association Study (GWAS) Consortium (2014).
Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.
J A M A Psychiatry,
71(7), 778-85.
https://doi.org/10.1001/jamapsychiatry.2014.528Buttenschøn, H. N., Jacobsen, I. S., Grynderup, M. B., Hansen, A. M.
, Kolstad, H. A., Kaerlev, L., Thomsen, J. F., Nordentoft, M., Silahtaroglu, A., Tommerup, N., Tümer, Z., Krogh, J.
, Børglum, A. D. & Mors, O. (2013).
An association study between the norepinephrine transporter gene and depression.
Psychiatric Genetics,
23(5), 217-221.
https://doi.org/10.1097/YPG.0000000000000003
