Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019).
Investigating the association between body fat and depression via Mendelian randomization.
Translational Psychiatry,
9(1), Article 184.
https://doi.org/10.1038/s41398-019-0516-4
Sørensen, H. J.
, Antonsen, S., Benros, M. E., Erlangsen, A.
, Albiñana, C., Nordentoft, M.
, Børglum, A. D., Mors, O., Werge, T.
, Mortensen, P. B., Hougaard, D., Webb, R. T.
& Agerbo, E. (2023).
School performance and genetic propensities for educational attainment and depression in the etiology of self-harm: a Danish population-based study.
Nordic Journal of Psychiatry,
77(2), 179-187.
https://doi.org/10.1080/08039488.2022.2078998
Soler Artigas, M., Sánchez-Mora, C., Rovira, P., Richarte, V., Garcia-Martínez, I., Pagerols, M.
, Demontis, D., Stringer, S., Vink, J. M.
, Børglum, A. D., Neale, B. M., Franke, B., Faraone, S. V., Casas, M., Ramos-Quiroga, J. A., Ribasés, M., ADHD Group of the Psychiatric Genomics Consortium, International Cannabis Consortium & International Cannabis Consortium (2020).
Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.
Molecular Psychiatry,
25(10), 2493-2503.
https://doi.org/10.1038/s41380-018-0339-3
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K.
, Grove, J., Albiñana, C., Geller, F., Bjurström, C. F.
, Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V.
, Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022).
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes.
Brain : a journal of neurology,
145(2), 555–568.
https://doi.org/10.1093/brain/awab260
Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T.
, Børglum, A., Mors, O., Nordentoft, M.
, Mortensen, P. B. & Hougaard, D. M. (2019).
Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders.
Translational Psychiatry,
9(1), Article 252.
https://doi.org/10.1038/s41398-019-0587-2
Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M. ... Daly, M. J. (2022).
Rare coding variants in ten genes confer substantial risk for schizophrenia.
Nature,
604(7906), 509-516.
https://doi.org/10.1038/s41586-022-04556-w
Severinsen, J., Als, T. D., Binderup, H., Wang, AG., Kruse, TA., Muir, WJ., Blackwood, DH.
, Mors, O. & Børglum, A. (2005).
Association analysis suggesting GPR24 as a shared susceptibility gene for bipolar affective disorder and schizophrenia. Abstract from XIII World Congress on Psychiatric Genetics 2005 Boston, USA.
Severinsen, J., Als, T. D., Binderup, H., Kruse, T. A., Wang, A. G., Muir, W. J., Blackwood, D. H. R.
, Mors, O. & Børglum, A. (2006).
Association analyses suggest GPR24 as a shared susceptibility gene for bipolar affective disorder and schizophrenia.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
141B, 524-533.
Severinsen, J., Bjarkam, C., Kiær-Larsen, S.
, Olsen, I. M., Nielsen, M. M.
, Blechingberg, J., Nielsen, A. L., Holm, I. E.
, Foldager, L., Young, B. D., Muir, W. J., Blackwood, D. HR.
, Corydon, T. J., Mors, O. & Børglum, A. (2006).
Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder. Molecular Psychiatry, 1126-1138.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16924267&itool=iconabstr&query_hl=1&itool=pubmed_docsum
Severinsen, J., Bjarkam, C., Kiær-Larsen, S.
, Olsen, I. M., Nielsen, M. M.
, Blechingberg, J., Nielsen, A. L., Holm, I. E.
, Foldager, L., Young, B. D., Muir, W. J., Blackwood, D. HR.
, Corydon, T. J., Mors, O. & Børglum, A. (2006).
Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder.. Abstract from XlV World Congress on Psychiatric Genetics, Caliari, Italy.
Severinsen, J., Binderup, H.
, Mors, O., Wang, A. G., Vang, M., Murray, V., Muir, W., Mckee, I., Kruse, T. A., Blackwood, D. HR., Ewald, H.
& Børglum, A. (2002).
Association study of candidate genes for susceptibility to schizophrenia and bipolar disorder on chromosome 22Q13. Abstract from X World Congress on Psychiatric Genetics, 2002, Bruxelles, Belgium.
Severinsen, J.
, Nyegaard, M., Bjarkam, C., Corydon, T. J.
, Olsen, I. M., Straarup, S., Nordentoft, M., Gurling, H. M.
, Mors, O. & Børglum, A. (2008).
Support for BRD1 as a suspectibility gene for both schizophrenia and bipolar affective disorder. Abstract from World Congress on Psychiatric Genetics XV, New York, United States.
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J.
, Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M.
, Mors, O., Børglum, A. D. ... Werge, T. (2019).
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment.
Nature Neuroscience,
22(3), 353-361.
https://doi.org/10.1038/s41593-018-0320-0
Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B.
, Grove, J., Kalkbrenner, A.
, Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M.
, Børglum, A. D., Werge, T., Nordentoft, M.
, Mortensen, P. B. & Agerbo, E. (2022).
Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism.
Autism Research,
15(1), 171-182.
https://doi.org/10.1002/aur.2629
Schaldemose, E. L., Horjales-Araujo, E.
, Demontis, D., Børglum, A. D., Svensson, P. & Finnerup, N. B. (2014).
No association of polymorphisms in the serotonin transporter gene with thermal pain sensation in healthy individuals.
Molecular Pain,
10(1), 76.
https://doi.org/10.1186/1744-8069-10-76
Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M.
, Lescai, F., Demontis, D., Kosmicki, J. A.
, Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., iPSYCH-Broad Consortium, Nordentoft, M.
, Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M. ... Daly, M. J. (2019).
Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants.
Nature Neuroscience,
22(12), 1961-1965.
https://doi.org/10.1038/s41593-019-0527-8
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R.
, Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U.
... Børglum, A. D. (2020).
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
Cell,
180(3), 568-584.e23.
https://doi.org/10.1016/j.cell.2019.12.036
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J.
, Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, T. & Ingason, A. (2023).
Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study.
The Lancet Psychiatry,
10(2), 129-138.
https://doi.org/10.1016/S2215-0366(23)00004-4
Saetre, P.
, Grove, J., Børglum, A., Mors, O., Werge, T. M., Andreassen, O. A., Vares, M., Agartz, I., Terenius, L. & Jönsson, E. G. (2012).
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
159B(8).
Rovira, P.
, Demontis, D., Sánchez-Mora, C., Zayats, T., Klein, M., Mota, N. R., Weber, H., Garcia-Martínez, I., Pagerols, M., Vilar-Ribó, L., Arribas, L., Richarte, V., Corrales, M., Fadeuilhe, C., Bosch, R., Martin, G. E., Almos, P., Doyle, A. E., Grevet, E. H. ... 23andMe Research Team (2020).
Shared genetic background between children and adults with attention deficit/hyperactivity disorder.
Neuropsychopharmacology,
45(10), 1617-1626.
https://doi.org/10.1038/s41386-020-0664-5
Ronda, V., Agerbo, E., Bleses, D., Mortensen, P. B., Børglum, A., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T.
& Rosholm, M. (2020).
Family disadvantage, gender, and the returns to genetic human capital. IZA Institute of Labor Economics. IZA Discussion Paper No. 13441
Ronda, V., Agerbo, E., Bleses, D., Mortensen, P. B., Børglum, A., Mors, O., Rosholm, M., Hougaard, D. M., Nordentoft, M. & Werge, T. (2022).
Family disadvantage, gender, and the returns to genetic human capital*.
Scandinavian Journal of Economics,
124(2), 550-578.
https://doi.org/10.1111/sjoe.12462
Rolland, T., Cliquet, F., Anney, R. J. L., Moreau, C., Traut, N., Mathieu, A., Huguet, G.
, Duan, J., Warrier, V., Portalier, S., Dry, L., Leblond, C. S., Douard, E., Amsellem, F., Malesys, S., Maruani, A., Toro, R.
, Børglum, A. D., Grove, J. ... Bourgeron, T. (2023).
Phenotypic effects of genetic variants associated with autism.
Nature Medicine,
29(7), 1671-1680.
https://doi.org/10.1038/s41591-023-02408-2
Rohde, P. D., Demontis, D., Arvidson, S. M. N., Madsen, L. S., Loeschcke, V.
, Sørensen, P., Børglum, A. & Kristensen, T. N. (2015).
Functional Insight From Fruit Flies on Human ADHD Candidate Genes. In
Genes, Brain, and Behavior 2015: 17th Annual Meeting of the International Behavioural and Neural Genetics Society (pp. 35).
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes.
Genetics (Print),
203(4), 1901-1913.
https://doi.org/10.1534/genetics.116.189498
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 5th International Conference on Quantitative Genetics , Madison, United States.
Rohde, P. D., Demontis, D., Castro Dias Cuyabano, B., Børglum, A. & Sørensen, P. (2016).
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. 1901-1913. Poster session presented at 2nd Annual Danish Bioinformatics Conference, Odense, Denmark.
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B.
, Grove, J., Maller, J., Samocha, K. E., Sanders, S. J., Ripke, S., Martin, J.
, Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D.
, Mortensen, P. B., Børglum, A. D. ... Als, T. D. (2016).
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
Nature Genetics,
48(5), 552–555.
https://doi.org/10.1038/ng.3529
Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D.-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N. ... The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011).
Genome-wide association study identifies five new schizophrenia loci.
Nature Genetics,
43(10), 969-976.
https://doi.org/10.1038/ng.940
Rietschel, M., Mattheisen, M., Degenhardt, F., Kahn, R. S., Linszen, D. H., Os, J. V., Wiersma, D., Bruggeman, R., Cahn, W., de Haan, L., Krabbendam, L., Myin-Germeys, I., Mühleisen, T. W., Kirsch, P., Esslinger, C., Herms, S.
, Demontis, D., Steffens, M., Strohmaier, J. ... Cichon, S. (2012).
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.
Molecular Psychiatry,
17(9), 906–917.
https://doi.org/10.1038/mp.2011.80
Ribasés, M., Mitjans, M., Hartman, C. A., Soler Artigas, M.
, Demontis, D., Larsson, H., Ramos-Quiroga, J. A., Kuntsi, J., Faraone, S. V.
, Børglum, A. D., Reif, A., Franke, B. & Cormand, B. (2023).
Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes.
Neuroscience and Biobehavioral Reviews,
153, Article 105313.
https://doi.org/10.1016/j.neubiorev.2023.105313
Rajkumar, A. P., Christensen, J. H., Mattheisen, M., Jacobsen, I., Bache, I.
, Pallesen, J., Grove, J., Qvist, P., Mcquillin, A., Gurling, H. M., Tümer, Z.
, Mors, O. & Børglum, A. D. (2015).
Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.
Bipolar Disorders (English Edition, Online),
17(2), 205-211.
https://doi.org/10.1111/bdi.12239
Rajkumar, A. P.
, Qvist, P., Lazarus, R.
, Lescai, F., Ju, J.
, Nyegaard, M., Mors, O., Børglum, A. D., Li, Q.
& Christensen, J. H. (2015).
Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq.
B M C Genomics,
16, 548.
https://doi.org/10.1186/s12864-015-1767-y
Rajkumar, A. P., Horsdal, H. T., Wimberley, T., Cohen, D.
, Mors, O., Børglum, A. D. & Gasse, C. (2017).
Endogenous and Antipsychotic-Related Risks for Diabetes Mellitus in Young People With Schizophrenia: A Danish Population-Based Cohort Study.
American Journal of Psychiatry,
174(7), 686-694.
https://doi.org/10.1176/appi.ajp.2016.16040442
Rajkumar, A. P., Qvist, P., Donskov, J. G., Lazarus, R.
, Pallesen, J., Nava, N., Winther, G., Liebenberg, N., Cour, S. H. L., Paternoster, V., Fryland, T., Palmfeldt, J., Fejgin, K., Mørk, A.
, Nyegaard, M., Pakkenberg, B., Didriksen, M.
, Nyengaard, J. R., Wegener, G. ... Børglum, A. D. (2020).
Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice.
Translational Psychiatry,
10, Article 239.
https://doi.org/10.1038/s41398-020-00914-2
Rajagopal, V. M., Agerbo, E., Timmermann, A., Børglum, A. & Demontis, D. (2017).
Genome-wide association study of dyslexia in the Danish population. Poster session presented at PhD Day 2017, Aarhus, Denmark.
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T.
, Mors, O., Hougaard, D. M.
, Mortensen, P. B. ... Demontis, D. (2022).
Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder.
Nature Genetics,
54(8), 1117-1124.
https://doi.org/10.1038/s41588-022-01143-7
Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G.
, Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M.
, Mors, O., Nordentoft, M., Werge, T.
... Demontis, D. (2023).
Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity.
Scientific Reports,
13, Article 429.
https://doi.org/10.1038/s41598-022-26845-0
Qvist, P., Huertas, P., Jimeno, S.
, Nyegaard, M., Hassan, M. J., Jackson, S. P.
& Børglum, A. (2011).
CtIP Mutations Cause Seckel and Jawad Syndromes.
P L o S Genetics,
7(10), e1002310.
https://doi.org/10.1371/journal.pgen.1002310
Qvist, P., Christensen, J. H., Vardya, I., Rajkumar, A. P., Mørk, A.
, Paternoster, V., Füchtbauer, E.-M., Pallesen, J., Fryland, T., Dyrvig, M.
, Hauberg, M. E., Lundsberg, B., Fejgin, K.
, Nyegaard, M., Jensen, K.
, Nyengaard, J. R., Mors, O., Didriksen, M.
& Børglum, A. D. (2017).
The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.
Biological Psychiatry,
82(1), 62-76.
https://doi.org/10.1016/j.biopsych.2016.08.037
Qvist, P., Rajkumar, A. P., Redrobe, J. P.
, Nyegaard, M., Christensen, J. H., Mors, O., Wegener, G., Didriksen, M.
& Børglum, A. D. (2017).
Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia.
Neurobiology of Learning and Memory,
141, 44-52.
https://doi.org/10.1016/j.nlm.2017.03.009
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J.
, Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018).
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice.
Scientific Reports,
8(1), 16486. Article 16486.
https://doi.org/10.1038/s41598-018-34729-5
Purves, K. L., Coleman, J. R. I.
, Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M.
, Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M.
, Mors, O. ... Eley, T. C. (2020).
A major role for common genetic variation in anxiety disorders.
Molecular Psychiatry,
25, 3292-3303.
https://doi.org/10.1038/s41380-019-0559-1
Power, R. A., Tansey, K. E.
, Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., Kutalik, Z., Lee, S. H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N. R., Arolt, V., Baune, B. T., Boomsma, D. I.
, Børglum, A. D., Castelao, E., Craddock, N. ... CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium (2017).
Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.
Biological Psychiatry,
81(4), 325–335.
https://doi.org/10.1016/j.biopsych.2016.05.010
Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J.
, Wang, J., Nordentoft, M., Werge, T. M.
, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J.
& Hollegaard, M. V. (2016).
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.
PLOS ONE,
11(4), e0153253. Article e0153253.
https://doi.org/10.1371/journal.pone.0153253
Pirastu, N., Cordioli, M., Nandakumar, P., Mignogna, G., Abdellaoui, A., Hollis, B., Kanai, M.
, Rajagopal, V. M., Parolo, P. D. B., Baya, N., Carey, C. E., Karjalainen, J.
, Als, T. D., Van der Zee, M. D., Day, F. R., Ong, K. K., Morisaki, T., de Geus, E., Bellocco, R. ... iPSYCH Consortium (2021).
Genetic analyses identify widespread sex-differential participation bias.
Nature Genetics,
53(5), 663-671.
https://doi.org/10.1038/s41588-021-00846-7
Pineda-Cirera, L., Shivalikanjli, A., Cabana-Domínguez, J.
, Demontis, D., Rajagopal, V. M., Børglum, A. D., Faraone, S. V., Cormand, B. & Fernàndez-Castillo, N. (2019).
Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder.
Translational Psychiatry,
9(1), Article 242.
https://doi.org/10.1038/s41398-019-0574-7