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Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T. M. ... Rademakers, R. (2018). Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet Neurology, 17(6), 548-558. https://doi.org/10.1016/S1474-4422(18)30126-1
Smith, A. H., Ovesen, P. L., Skeldal, S., Yeo, S., Jensen, K. P., Olsen, D., Diazgranados, N., Zhao, H., Farrer, L. A., Goldman, D., Glerup, S., Kranzler, H. R., Nykjaer, A. & Gelernter, J. (2018). Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2. Alcoholism: Clinical and Experimental Research, 42(12), 2337-2348. https://doi.org/10.1111/acer.13890
Goettsch, C., Kjølby, M. F. & Aikawa, E. (2018). Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(1), 19-25. https://doi.org/10.1161/ATVBAHA.117.310292
Parrish, D. C., Francis Stuart, S. D., Olivas, A., Wang, L., Nykjaer, A., Ripplinger, C. M. & Habecker, B. A. (2018). Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility. A J P: Heart and Circulatory Physiology (Online), 314(3), H415-H423. https://doi.org/10.1152/ajpheart.00300.2017
Uchiyama, K., Tomita, M., Yano, M., Chida, J., Hara, H., Das, N. R., Nykjaer, A. & Sakaguchi, S. (2017). Prions amplify through degradation of the VPS10P sorting receptor sortilin. PLoS Pathogens, 13(6), e1006470. Article e1006470. https://doi.org/10.1371/journal.ppat.1006470
Goettsch, C., Hutscheson, JD., Hagita, S., Rogers, M., Creager, MD., Pham, T., Choi, J., Mlynarchik, AK., Pieper, B., Kjølby, M. F., Aikawa, M. & Aikawa, E. (2016). A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis, 251, 109-118. https://doi.org/10.1016/j.atherosclerosis.2016.06.011
Goettsch, C., Hutscheson, JD., Aikawa, M., Iwata, H., Pham, T., Nykjær, A., Kjølby, M. F., Rogers, M., Michel, T., Shibasaki, M., Hagita, S., Kramann, R., Rader, D. J., Libby, P., Singh, SA. & Aikawa, E. (2016). Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. Journal of Clinical Investigation, 126(4), 1323. https://doi.org/10.1172/JCI80851
Lisi, S., Madsen, P., Botta, R., Petersen, C. M., Nykjær, A., Latrofa, F., Vitti, P. & Marinò, M. (2015). ABSENCE OF A THYROID PHENOTYPE IN SORTILIN-DEFICIENT MICE. Endocrine Practice, 21(9), 981-985. https://doi.org/10.4158/EP15697.OR
Lewin, G. R. & Nykjaer, A. (2014). Pro-neurotrophins, sortilin, and nociception. The European journal of neuroscience, 39(3), 363-74. https://doi.org/10.1111/ejn.12466
Cases, O., Perea-Gomez, A., P. Aguiar, D., Nykjær, A., Amsellem, S., Chandellier, J., Umbhauer, M., Cereghini, S., Madsen, M., Collignon, J., Verroust, P. J., Riou, J.-F., E. Creuzet, S. & Kozyraki, R. (2013). Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head. Journal of Biological Chemistry, 288(23), 16655-70. https://doi.org/10.1074/jbc.M113.451070
Capsoni, S., Amato, G., Vignone, D., Criscuolo, C., Nykjaer, A. & Cattaneo, A. (2013). Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation. Biochemical and Biophysical Research Communications, 431(3), 579-85. https://doi.org/10.1016/j.bbrc.2013.01.007
Burgert, T., Schmidt, V., Caglayan, S., Lin, F., Füchtbauer, A., Füchtbauer, E.-M., Nykjaer, A., Carlo, A.-S. & Willnow, T. E. (2013). SORLA-Dependent and -Independent Functions for PACS1 in Control of Amyloidogenic Processes. Molecular and Cellular Biology, 33(21), 4308-4320. https://doi.org/10.1128/MCB.00628-13
Carlo, A.-S., Gustafsen, C., Mastrobuoni, G., Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M., Nykjaer, A., Herz, J., Heeren, J., Kempa, S., Petersen, C. M. & Willnow, T. E. (2013). The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain. Journal of Neuroscience, 33(1), 358-70. https://doi.org/10.1523/JNEUROSCI.2425-12.2013
Gass, J., Lee, W. C., Cook, C., Finch, N., Stetler, C., Jansen-West, K., Lewis, J., Link, C. D., Rademakers, R., Nykjær, A. & Petrucelli, L. (2012). Progranulin regulates neuronal outgrowth independent of Sortilin. Molecular Neurodegeneration, 7, 33. https://doi.org/10.1186/1750-1326-7-33
Siao, C.-J., Lorentz, C. U., Kermani, P., Marinic, T., Carter, J. D., McGrath, K., Padow, V. A., Mark, W., Falcone, D. J., Cohen-Gould, L., Parrish, D. C., Habecker, B. A., Nykjaer, A., Ellenson, L. H., Tessarollo, L. & Hempstead, B. L. (2012). ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation. The Tohoku Journal of Experimental Medicine, 209(12), 2291-305. https://doi.org/10.1084/jem.20111749
Schmidt, V., Baum, K., Lao, A., Rateitschak, K., Schmitz, Y., Teichmann, A., Wiesner, B., Petersen, C. M., Nykjaer, A., Wolf, J., Wolkenhauer, O. & Willnow, T. E. (2012). Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease. E M B O Journal, 31(1), 187-200. https://doi.org/10.1038/emboj.2011.352
Shulga, A., Magalhães, A. C., Autio, H., Plantman, S., di Lieto, A., Nykjær, A., Carlstedt, T., Risling, M., Arumäe, U., Castrén, E. & Rivera, C. (2012). The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons. Journal of Neuroscience, 32(5), 1757-70. https://doi.org/10.1523/JNEUROSCI.3282-11.2012
Dinet, V., An, N., Ciccotosto, G. D., Bruban, J., Maoui, A., Bellingham, S. A., Hill, A. F., Andersen, O. M., Nykjaer, A., Jonet, L., Cappai, R. & Mascarelli, F. (2011). APP involvement in retinogenesis of mice. Acta Neuropathologica, 121(3), 351-63. https://doi.org/10.1007/s00401-010-0762-2