Publications

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Binda, K. H., Real, C. C., Simonsen, M. T., Grove, E. K., Bender, D., Gjedde, A., Brooks, D. J. & Landau, A. M. (2025). Acute transcutaneous auricular vagus nerve stimulation modulates presynaptic SV2A density in healthy rat brain: An in vivo microPET study. Psychophysiology, 62(1), Article e14709. https://doi.org/10.1111/psyp.14709

Bender, D. (2025). New Radiopharmaceutical Tools in Imaging. Seminars in Nuclear Medicine, 55(5), 789-794. https://doi.org/10.1053/j.semnuclmed.2025.05.002

Pedersen, M. A., Munk, O. L., Dias, A. H., Steffensen, J. H., Møller, A. L., Johnsson, A. L., Hansen, K. V., Bender, D., Jakobsen, S., Busk, M., Gormsen, L. C., Tramm, T., Borgquist, S. & Vendelbo, M. H. (2024). Dynamic whole-body [¹⁸F]FES PET/CT increases lesion visibility in patients with metastatic breast cancer. EJNMMI research, 14(1), 24. Article 24. https://doi.org/10.1186/s13550-024-01080-y

Thomsen, M. B., Landau, A. M., Bender, D. & Cumming, P. (2023). Autoradiographic characterization of [¹⁸F]PSMA-1007 binding in rat brain. Synapse, 77(6), Article e22280. https://doi.org/10.1002/syn.22280

Munk, D. E., Vendelbo, M. H., Kirk, F. T., Rewitz, K. S., Bender, D. A., Vase, K. H., Munk, O. L., Vilstrup, H., Ott, P. & Sandahl, T. D. (2023). Distribution of non-ceruloplasmin-bound copper after i.v. ⁶⁴Cu injection studied with PET/CT in patients with Wilson disease. JHEP Reports, 5(11), Article 100916. https://doi.org/10.1016/j.jhepr.2023.100916

Arjmand, S., Bender, D., Jakobsen, S., Wegener, G. & Landau, A. M. (2023). Peering into the Brain's Estrogen Receptors: PET Tracers for Visualization of Nuclear and Extranuclear Estrogen Receptors in Brain Disorders. Biomolecules, 13(9), Article 1405. https://doi.org/10.3390/biom13091405

Horsager, J., Okkels, N., Fedorova, T. D., Knudsen, K., Skjærbæk, C., Van Den Berge, N., Jacobsen, J., Munk, O. L., Danielsen, E. H., Bender, D., Brooks, D. J. & Borghammer, P. (2022). [ 18F]FEOBV positron emission tomography may not be a suitable method to measure parasympathetic denervation in patients with Parkinson's disease. Parkinsonism & Related Disorders, 104, 21-25. https://doi.org/10.1016/j.parkreldis.2022.09.016

Hansen, S. B. & Bender, D. (2022). Advancement in Production of Radiotracers. Seminars in Nuclear Medicine, 52(3), 266-275. https://doi.org/10.1053/j.semnuclmed.2021.10.003

Horsager, J., Okkels, N., Van Den Berge, N., Jacobsen, J., Schact, A., Munk, O. L., Vang, K., Bender, D., Brooks, D. J. & Borghammer, P. (2022). In vivo vesicular acetylcholine transporter density in human peripheral organs: an [ 18F]FEOBV PET/CT study. EJNMMI research, 12(1), Article 17. https://doi.org/10.1186/s13550-022-00889-9

Chang, N. H. S., Kumakura, Y., Møller, A., Linnet, J., Bender, D., Doudet, D. J., Vafaee, M. S. & Gjedde, A. (2022). On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum. Brain Imaging and Behavior, 16(1), 355-365. https://doi.org/10.1007/s11682-021-00509-5

Sandahl, T. D., Gormsen, L. C., Kjærgaard, K., Vendelbo, M., Munk, D. E., Munk, O. L., Bender, D., Keiding, S., Vase, K. H., Frisch, K., Vilstrup, H. V. A. & Ott, P. (2022). The pathophysiology of Wilson’s disease visualized: A human ⁶⁴Cu PET study. Hepatology, 75(6), 1461-1470. https://doi.org/10.1002/hep.32238

Vibholm, A. K., Dietz, M. J., Beniczky, S., Christensen, J., Højlund, A., Jacobsen, J., Bender, D., Møller, A. & Brooks, D. J. (2021). Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [¹⁸F]GE-179 positron emission tomography. Epilepsia, 62(12), 2899-2908. https://doi.org/10.1111/epi.17074

Andersen, V. L., Soerensen, M. A., Dam, J. H., Langkjaer, N., Petersen, H., Bender, D. A., Fugloe, D. & Huynh, T. H. V. (2021). GMP production of 6-[¹⁸F]Fluoro-l-DOPA for PET/CT imaging by different synthetic routes: a three center experience. EJNMMI Radiopharmacy and Chemistry, 6, Article 21. https://doi.org/10.1186/s41181-021-00135-y

Maurer, A., Leonov, A., Ryazanov, S., Herfert, K., Kuebler, L., Buss, S., Schmidt, F., Weckbecker, D., Linder, R., Bender, D., Giese, A., Pichler, B. J. & Griesinger, C. (2020). ¹¹C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier. ChemMedChem, 15(5), 411-415. https://doi.org/10.1002/cmdc.201900689

Nielsen, K. M., Jørgensen, N. P., Kyneb, M. H., Borghammer, P., Meyer, R. L., Thomsen, T. R., Bender, D., Jensen, S. B., Nielsen, O. L. & Alstrup, A. K. O. (2018). Preclinical evaluation of potential infection-imaging probe [⁶⁸Ga]Ga-DOTA-K-A9 in sterile and infectious inflammation. Journal of Labelled Compounds and Radiopharmaceuticals, 61(10), 780-795. https://doi.org/10.1002/jlcr.3640

Jørgensen, N. P., Alstrup, A. K. O., Mortensen, F. V., Knudsen, K., Jakobsen, S., Madsen, L. B., Bender, D., Breining, P., Petersen, M. S., Schleimann, M. H., Dagnæs-Hansen, F., Gormsen, L. C. & Borghammer, P. (2017). Cholinergic PET imaging in infections and inflammation using 11C-donepezil and 18F-FEOBV. European Journal of Nuclear Medicine and Molecular Imaging, 44(3), 449–458. https://doi.org/10.1007/s00259-016-3555-6

Horsager, J., Lausten, S. B., Bender, D., Munk, O. L. & Keiding, S. (2017). Hepatic metabolism of 11C-methionine and secretion of 11C-protein measured by PET in pigs. American Journal of Nuclear Medicine and Molecular Imaging, 7(4), 167-173. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596319/pdf/ajnmmi0007-0167.pdf

Nielsen, K. M., Bender, D., Nielsen, O. L., Jensen, S. B. & Alstrup, A. K. O. (2017). In vivo stability evaluation of 68Ga-labelled dodecapeptide for bacterial infection imaging. Poster session presented at 22nd International Symposium on Radiopharmaceutical Sciences, Dresden, Germany.

Marzano, C., Jakobsen, S., Salinas, C., Tang, S. P., Bender, D., Passchier, J. & Plisson, C. (2017). Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system. Journal of Labelled Compounds and Radiopharmaceuticals, 60(12), 556-565. https://doi.org/10.1002/jlcr.3535

Dam, J. H., Bender, D., Peters, D. & Någren, K. (2016). [¹¹C]NS9531, [¹¹C]NS9762 and [¹¹C]NS6417, specific SERT tracers: pre-clinical evaluation in pigs and optimization of synthesis conditions using [¹¹C]methyl triflate. Nuclear Medicine and Biology, 43(1), 42-51. https://doi.org/10.1016/j.nucmedbio.2015.10.004

Nielsen, K. M., Kyneb, M. H., Alstrup, A. K. O., Jensen, J. J., Bender, D., Schønheyder, H. C., Afzelius, P., Nielsen, O. L. & Jensen, S. B. (2016). (68)Ga-labeled phage-display selected peptides as tracers for positron emission tomography imaging of Staphylococcus aureus biofilm-associated infections: Selection, radiolabelling and preliminary biological evaluation. Nuclear Medicine and Biology, 43(10), 593-605. https://doi.org/10.1016/j.nucmedbio.2016.07.002

Tentillier, N., Etzerodt, A., Olesen, M. N., Rizalar, F. S., Jacobsen, J., Bender, D., Moestrup, S. K. & Romero-Ramos, M. (2016). Anti-Inflammatory Modulation of Microglia via CD163-Targeted Glucocorticoids Protects Dopaminergic Neurons in the 6-OHDA Parkinson's Disease Model. The Journal of neuroscience, 36(36), 9375-90. https://doi.org/10.1523/JNEUROSCI.1636-16.2016

Afzelius, P., Nielsen, O. L., Alstrup, A. K. O., Bender, D., Leifsson, P. S., Jensen, S. B. & Schønheyder, HC. (2016). Biodistribution of the radionuclides (18)F-FDG, (11)C-methionine, (11)C-PK11195, and (68)Ga-citrate in domestic juvenile female pigs and morphological and molecular imaging of the tracers in hematogenously disseminated Staphylococcus aureus lesions. American Journal of Nuclear Medicine and Molecular Imaging, 6(1), 42-58. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749504/pdf/ajnmmi0006-0042.pdf

Afzelius, P., Nielsen, O. L., Alstrup, A. K. O., Bender, D., Leifsson, P. S., Jensen, S. B. & Schønheyder, H. C. (2016). Biodistribution of the radionuclides 18F-FDG, 11C-methionine, 11C-PK11195, and 68Ga-citrate in domestic juvenile female pigs and morphological and molecular imaging of the tracers in hematogenously disseminated Staphylococcus aureus lesions. Poster session presented at Dansk Radiologisk Selskabs 11. årsmøde med Dansk Selskab for Klinisk Fysiologi og Nuklearmedicin og Dansk Ultralyddiagnostisk Selskab, Odense, Denmark.

Nielsen, M. S., GLUD, AN., Møller, A., Mogensen, P., Bender, D., Sørensen, J. C., Doudet, D. & Bjarkam, C. R. (2016). Continuous MPTP intoxication in the Göttingen minipig results in chronic parkinsonian deficits. Acta Neurobiologiae Experimentalis, 76(3), 199-211. https://doi.org/10.21307/ane-2017-020

Lou, H. O. C., Rosenstand, A., Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U., Hansen, K. V. & Møller, A. (2016). Exogenous dopamine reduces GABA receptor availability in the human brain. Brain and Behavior, 6(7), e00484. Article e00484. https://doi.org/10.1002/brb3.484

Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016). In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Brain, 139(7), 2039-2049. https://doi.org/10.1093/brain/aww098

Stokholm, M. G., Høyer, S., Borre, M., Bender, D., Jakobsen, S., Frøkiær, J. & Borghammer, P. (2016). Molecular imaging of cholinergic processes in prostate cancer using (11)C-donepezil and (18)F-FEOBV. European Journal of Nuclear Medicine and Molecular Imaging, 43(5), 906-910. https://doi.org/10.1007/s00259-015-3143-1

Tvilling, L., Glud, A. N., Orlowski, D., Jakobsen, J., Pedersen, M., Ettrup, K. S. E., West, M. J., Bender, D., Bjarkam, C. & Sørensen, J. C. H. (2016). The anatomy and neurohistology of the minipig pituitary. Poster session presented at Neuroscience 2016, San Diego, United States.

Afzelius, P., Alstrup, A. K. O., Schønheyder, H. C., Borghammer, P., Jensen, S. B., Bender, D. & Nielsen, O. L. (2016). Utility of (11)C-methionine and (11)C-donepezil for imaging of Staphylococcus aureus induced osteomyelitis in a juvenile porcine model: comparison to autologous (111)In-labelled leukocytes, (99m) Tc-DPD, and (18)F-FDG. American Journal of Nuclear Medicine and Molecular Imaging, 6(6), 286-300.

Eichendorff, S., Svendsen, P., Bender, D., Keiding, S., Christensen, E. I., Deleuran, B. & Moestrup, S. K. (2015). Biodistribution and PET Imaging of a Novel [(68)Ga]-Anti-CD163-Antibody Conjugate in Rats with Collagen-Induced Arthritis and in Controls. Molecular Imaging and Biology, 17(1), 87-93. https://doi.org/10.1007/s11307-014-0768-6

Jødal, L., Hansen, S. B., Jensen, S. B., Bender, D., Alstrup, A. K. O., Afzelius, P. & Nielsen, O. L. (2015). PET tracer uptake kinetics in inflammation and infection imaging using a porcine osteomyelitis model – preliminary results. Poster session presented at Dansk Selskab for Medicinsk Fysik, Nyborg, Denmark.

Vibholm, A. K., Landau, A. M., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Simonsen, M., Bender, D., Møller, A., Pavese, N., Sørensen, J. C. H. & Brooks, D. (2015). Preclinical in-vivo imaging of activated NMDA receptor ion channels with the novel radioligand 18F-GE179. Abstract from Pd.d.-dag, Aarhus, Denmark.

Vase, K. H., Peters, D., Nielsen, E. Ø., Alstrup, A. K. O. & Bender, D. (2014). [11C]NS8880, a promising PET radiotracer targeting the norepinephrine transporter. Nuclear Medicine and Biology, 41, 758-764. https://doi.org/10.1016/j.nucmedbio.2014.06.004

Nielsen, O. L., Afzelius, P., Bender, D., Schønheyder, H. C., Leifsson, P. S., Nielsen, K. M., Larsen, J. O., Jensen, S. B. & Alstrup, A. K. O. (2014). Comparison of autologous 111In-leukocytes, 18F-FDG, 11C-methionine, 11C-PK11195 and 68Ga-citrate for diagnostic nuclear imaging in a juvenile porcine haematogenous Staphylococcus aureus osteomyelitis model. Abstract from SPECT and PET imaging in porcine inflammation and infection models, København, Denmark.

Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P. (2014). In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses. Journal of Nuclear Medicine, 55(11), 1818-24. https://doi.org/10.2967/jnumed.114.143859

Winterdahl, M., Audrain, H., Landau, A. M., Smith, D. F., Bonaventure, P., Shoblock, J. R., Carruthers, N., Swanson, D. & Bender, D. (2014). PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs. Journal of Nuclear Medicine, 55(4), 635-9. https://doi.org/10.2967/jnumed.113.125351

Glerup, S., Olsen, D., Vægter, C. B., Gustafsen, C., Sjøgaard, S., Hermey, G., Kjølby, M. F., Jensen, S. M., Ulrichsen, M., Hansen, S. B., Skeldal, S., Fjorback, A. N., Nyengaard, J. R., Jacobsen, J., Bender, D., Bjarkam, C. R., Sørensen, E. S., Füchtbauer, E.-M., Eichele, G. ... Nykjær, A. (2014). SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia. Neuron, 82(5), 1074–1087. https://doi.org/10.1016/j.neuron.2014.04.022

Afzelis, P., Jensen, S. B., Alstrup, A. K. O., Larsen, J. O., Schønheyder, H. C., Nielsen, K. M., Jødal, L., Hansen, S. B. & Bender, D. (2013). Grise-osteomyelitis-model: hvilke sporstoffer?. Abstract from Dansk Selskab for Klinisk Fysiologi og Nuklearmedicin, Korsør, Denmark.

Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.