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Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis.
Frontiers in Genetics,
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Phenotypic effects of genetic variants associated with autism.
Nature Medicine,
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Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample.
Translational Psychiatry,
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Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios.
Nature Communications,
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Novel polymorphisms in the somatostatin receptor 5 (SSTR5) gene associated with bipolar affective disorder.
Molecular Psychiatry,
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No signature of Y chromosomal resemblance between possible descendants of the Cimbri in Denmark and Northern Italy.
American Journal of Physical Anthropology,
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No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study.
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Nordrenalin transportergenet er et kandidatgen for panikangst. Poster session presented at Psykiatriens 5. Forskningsdag, Risskov, Denmark.
Hjorthøj, C., Uddin, M. J.
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No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder.
Psychological Medicine,
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No association of polymorphisms in the serotonin transporter gene with thermal pain sensation in healthy individuals.
Molecular Pain,
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No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia.
Psychiatric Genetics,
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Ejerskov, C., Krogh, K., Børglum, A., Østergaard, J. R. & Haagerup, A. (2018).
NF1 and the gastrointestinal canal: A high prevalence of gastrointestinal symptoms correlated to constipation.. Poster session presented at 18th European Neurofibromatosis Meeting, Paris, France.
Bukowski, L., Chernomorchenko, A. M. F., Starnawska, A., Mors, O., Staunstrup, N. H., Børglum, A. D. & Qvist, P. (2020).
Neuropsin in mental health.
Journal of Physiological Sciences,
70(1), Article 26.
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Mortensen, P. B., Pedersen, C. B., McGrath, J. J., Hougaard, D. M., Nørgaard-Petersen, B.
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Neonatal antibodies to infectious agents and risk of bipolar disorder: a population-based case-control study.
Bipolar Disorders,
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Andersen, P. S., Havndrup, O., Bundgaard, H., Moolman-Smook, J. C., Larsen, L. A.
, Mogensen, J., Brink, P. A.
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Myosin light chain mutations in familial hypertrophic cardiomyopathy: phenotypic presentation and frequency in Danish and South African populations.
Journal of Medical Genetics,
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Nyegaard, M., Overgaard, M. T., Søndergaard, M., Vranas, M., Behr, E. R., Hildebrandt, L., Lund, J., Hedley, P. L., Camm, A. J., Wettrell, G., Fosdal, I., Christiansen, M.
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Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death.
American Journal of Human Genetics,
91(4), 703-12.
https://doi.org/10.1016/j.ajhg.2012.08.015
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Multi-PGS enhances polygenic prediction by combining 937 polygenic scores.
Nature Communications,
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Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
Nature Medicine,
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Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.
Nature Genetics,
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
American Journal of Human Genetics,
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Qvist, P., Rajkumar, A. P., Redrobe, J. P.
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Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia.
Neurobiology of Learning and Memory,
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Saetre, P.
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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: no consistent evidence for an association in the Nordic population.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
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Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes.
Genetic Epidemiology,
35(5), 318-32.
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Nudel, R., Thompson, W. K.
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Maternal pregnancy-related infections and autism spectrum disorder-the genetic perspective.
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Mortensen, P. B., Pedersen, CB., Hougaard, DM., Norgaard-Petersen, B.
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Maternal antibodies to cytomegalovirus and schizophrenia risk. Abstract from 13th International Congress on Schizophrenia Research (ICOSR), Colorado Springs, United States.
Gregersen, N., Buttenschøn, H. N., Atli Dahl, H.
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Markers on chromosome 19p13 associated with panic disorder.
XVIIIth World Congress on Psychiatric Genetics. Book of abstracts., 288-289.
Gregersen, N., Buttenschøn, H. N., Dahl, HA.
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, Børglum, A. & Mors, O. (2011).
Markers on chromosome 19p13 are associated with panic disorder. Poster session presented at PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Denmark.
Børglum, A., Nyegaard, M., Kvistgaard, AB., Mullaart, E., Uitterlinden, AG., Vijg, J. & Kruse, T. A. (1997).
Mapping of 34 minisatellite loci resolved by two-dimensional DNA typing. Cytogenetic and Genome Research,
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Nature,
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Bolund, A. C. S., Starnawska, A., Miller, M. R.
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Lung function discordance in monozygotic twins and associated differences in blood DNA methylation.
Clinical Epigenetics (Print),
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Christensen, U., Møller-Larsen, S., Nyegaard, M., Haagerup, A., Hedemand, A., Brasch-Andersen, C., Kruse, T.
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Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21.
Human Genetics,
126(4), 549-557.
Nexø, B. A., Vogel, U.
, Olsen, A., Nyegaard, M., Bukowy, Z., Rockenbauer, E.
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, Overvad, K., Tjønneland, A.
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Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP. B M C Medical Genetics,
9(56), 1-12.
https://doi.org/10.1186/1471-2350-9-56
Marcheco, T. B., Torralbas, M., Flint, T., El Daoud, A., Gonzalez, L., Blanco, L., Ewald, H.
, Børglum, A., Kruse, T. A. & Mors, O. (2005).
Linkage analyses in candidate regions for bipolar affective disorder in a large and complex pedigree from the Holguin region in Eastern Cuba.
Cuban J. Hum. Genet.
Teruel, B. M., Torralbas, M.
, Zacharov, T. F., Daoud, A. E., Gonzalez, L., Blanco, L.
, Ewald, H. L., Børglum, A., Kruse, T.
& Mors, O. (2007).
Linkage analyses in candidate regions for bipolar affective disorder in a large and complex pedigree from the Holguin region in Eastern Cuba.
Revista Cubana de Genetica Comunitaria,
1(1), 37-43.
Haubek, D., Gjørup, H., Jensen, L. G., Juncker, I., Nyegaard, M., Børglum, A., Poulsen, S. & Hertz, J. M. (2011).
Limited phenotypic variation of hypocalcified amelogenesis imperfecta in a danish five-generation family with a novel FAM83H nonsense mutation.
International Journal of Paediatric Dentistry (Print),
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Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, M., Hougaard, D. M., Werge, T.
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction.
American Journal of Human Genetics,
108(6), 1001-1011.
https://doi.org/10.1016/j.ajhg.2021.04.014
Bulik-Sullivan, B. K., Loh, P.-R., Finucane, H. K., Ripke, S.
, Yang, J., Patterson, N., Daly, M. J., Price, A. L., Neale, B. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium (Anders Børglum and Ole Mors, members of -) (2015).
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nature Genetics,
47(3), 291–295.
https://doi.org/10.1038/ng.3211
Donskov, J. G., Starnawska, A., Pallesen, J., Grove, J., Børglum, A. & Qvist, P. (2021).
Large-scale genomic data-mining implicates dysregulated nuclear receptor-mediated signaling in mental illness.
Journal of Translational Genetics and Genomics,
5(2), 136-162.
https://doi.org/10.20517/jtgg.2021.12
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R.
, Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U.
... Børglum, A. D. (2020).
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
Cell,
180(3), 568-584.e23.
https://doi.org/10.1016/j.cell.2019.12.036
Lauritsen, M. B., Børglum, A., Betancur, C., Philippe, A., Kruse, T. A., Leboyer, M.
& Ewald, H. (2002).
Investigation of two variants in the DOPA decarboxylase gene in patients with autism.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
114(4), 466-70.
https://doi.org/10.1002/ajmg.10379
Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019).
Investigating the association between body fat and depression via Mendelian randomization.
Translational Psychiatry,
9(1), Article 184.
https://doi.org/10.1038/s41398-019-0516-4
Yang, Z., Wu, H., Lee, P. H., Tsetsos, F., Davis, L. K., Yu, D., Lee, S. H.
, Dalsgaard, S., Haavik, J., Barta, C., Zayats, T., Eapen, V., Wray, N. R., Devlin, B., Daly, M., Neale, B.
, Børglum, A. D., Crowley, J. J., Scharf, J. ... Paschou, P. (2021).
Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum.
Biological Psychiatry,
90(5), 317-327.
https://doi.org/10.1016/j.biopsych.2020.12.028
Debost, J.-C., Petersen, L., Grove, J., Khashan, A.
, Henriksen, T., Mors, O., Hollegaard, M., Hougaard, D.
, Nyegaard, M., Børglum, A. & Mortensen, P. B. (2015).
Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia.
Psychoneuroendocrinology,
60, 18-27.
https://doi.org/10.1016/j.psyneuen.2015.05.013
Treur, J. L.
, Demontis, D., Smith, G. D., Sallis, H., Richardson, T. G., Wiers, R. W.
, Børglum, A. D., Verweij, K. J. H. & Munafò, M. R. (2021).
Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.
Addiction Biology,
26(1), Article e12849.
https://doi.org/10.1111/adb.12849
Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, T., Hougaard, D. M., Nordentoft, M.
, Mors, O., Mortensen, P. B., Petersen, L. V. & Dalsgaard, S. (2023).
Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study.
The American Journal of Psychiatry (Spanish Edition),
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https://doi.org/10.1176/appi.ajp.21111105
Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M. ... Koenen, K. C. (2019).
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Nature Communications,
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https://doi.org/10.1038/s41467-019-12576-w