Foldager, L., Pedersen, C. B., Nyegaard, M., Zacharov, T. F., Nordentoft, M., Werge, T., Hougaard, DM., Sørensen, K. M.
, Mortensen, P. B., Mors, O. & Børglum, A. (2010).
Conditional logic regression: identifying SNP interactions from individually time-matched case-control data.
XVIIIth World Congress on Psychiatric Genetics. Book of abstracts., 202-203.
Debost, J.-C., Debost, M.
, Grove, J., Mors, O., Hougaard, D. M.
, Børglum, A. D., Mortensen, P. B. & Petersen, L. (2017).
COMT Val158Met and MTHFR C677T moderate risk of schizophrenia in response to childhood adversity.
Acta Psychiatrica Scandinavica,
136(1), 85-95.
https://doi.org/10.1111/acps.12761
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M.
, Hansen, C. S., Hedley, P. L.
, Kanters, J. K., Nielsen, J., Theisen, M.
, Mors, O., Kennedy, J.
, Als, T. D., Demur, A. B., Nordentoft, M.
, Børglum, A., Mortensen, P. B., Werge, T. M., Hougaard, D. M.
& Christiansen, M. (2018).
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes.
PLOS ONE,
13(12), Article e0208829.
https://doi.org/10.1371/journal.pone.0208829
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J.
, Pedersen, C., Hougaard, D. M.
, Børglum, A. D., Nordentoft, M.
, Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, T. (2022).
Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders.
JAMA Psychiatry,
79(1), 59-69.
https://doi.org/10.1001/jamapsychiatry.2021.3392
Steinberg, S., de Jong, S., Andreassen, O. A., Werge, T.
, Børglum, A. D., Mors, O., Mortensen, P. B., Gustafsson, O., Costas, J., Pietiläinen, O. P. H.
, Demontis, D., Papiol, S., Huttenlocher, J., Mattheisen, M., Breuer, R., Vassos, E., Giegling, I., Fraser, G., Walker, N. ... Irish Schizophrenia Genomics Consortium (2011).
Common Variants at VRK2 and TCF4 Conferring Risk of Schizophrenia.
Human Molecular Genetics,
20(20), 4076-81.
https://doi.org/10.1093/hmg/ddr325
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J.
, Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I. ... GROUP (2014).
Common variant at 16p11.2 conferring risk of psychosis.
Molecular Psychiatry,
19(1), 108-114.
https://doi.org/10.1038/mp.2012.157
Hauberg, M. E., Creus-Muncunill, J., Bendl, J., Kozlenkov, A., Zeng, B., Corwin, C., Chowdhury, S., Kranz, H., Hurd, Y. L., Wegner, M.
, Børglum, A. D., Dracheva, S., Ehrlich, M. E., Fullard, J. F. & Roussos, P. (2020).
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.
Nature Communications,
11, Article 5581.
https://doi.org/10.1038/s41467-020-19319-2
Mogensen, J., Perrot, A., Andersen, P. S., Havndrup, O., Klausen, I. C., Christiansen, M.
, Bross, P., Egeblad, H., Bundgaard, H., Osterziel, K. J., Haltern, G., Lapp, H., Reinecke, P.
, Gregersen, N. & Børglum, A. D. (2004).
Clinical and genetic characteristics of alpha cardiac actin gene mutations in hypertrophic cardiomyopathy.
Journal of Medical Genetics,
41(1), e10.
Hertz, J. M., Børglum, A. D., Brandt, C. A.
, Flint, T. & Bisgaard, C. (1994).
Charcot-Marie-Tooth disease type 1A: the parental origin of a de novo 17p11.2-p12 duplication.
Clinical Genetics,
46(4), 291-4.
Agerbo, E., Mortensen, P. B., Wiuf, C. H., Pedersen, MS., Hollegaard, M., Demiontis, D.
, Børglum, A., Hougaard, D.
, Mors, O. & Pedersen, CB. (2011).
Can SNP-variation across the whole-genome and across candidate genes explain the excess schizophrenia risk in offspring of parents with a severe psychiatric disorder?. Abstract from 13th International Congress on Schizophrenia Research (ICOSR), Colorado Springs, United States.
Hodgson, K., Coleman, J. R. I., Hagenaars, S. P., Purves, K. L., Glanville, K., Choi, S. W., O'Reilly, P., Breen, G., Lewis, C. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2020).
Cannabis use, depression and self-harm: phenotypic and genetic relationships.
Addiction,
115(3), 482-492.
https://doi.org/10.1111/add.14845
Pedersen, C. B., Demontis, D.
, Pedersen, M. S., Agerbo, E., Mortensen, P. B., Børglum, A., Hougaard, D.
, Mors, O. & Cantor-Graae, E. (2010).
Can genetic diversity explain the increased risk of schizophrenia among second generation immigrants?. Abstract from 2nd Biennial Schizophrenia International Research Conference, Florence, Italy.
Nyegaard, M., Demontis, D., Foldager, L., Hedemand, A., Flint, T. J., Sørensen, K. M., Andersen, P. S., Nordentoft, M., Werge, T.
, Pedersen, C. B., Hougaard, D. M.
, Mortensen, P. B., Mors, O. & Børglum, A. D. (2010).
CACNA1C (rs1006737) is associated with schizophrenia.
Molecular Psychiatry,
15(2), 119-21.
https://doi.org/10.1038/mp.2009.69
Starnawska, A., Demontis, D., Pen, A., Hedemand, A., Nielsen, A. L., Staunstrup, N. H., Grove, J., Als, T. D., Jarram, A., O'Brien, N. L.
, Mors, O., McQuillin, A.
, Børglum, A. D. & Nyegaard, M. (2016).
CACNA1C hypermethylation is associated with bipolar disorder.
Translational Psychiatry,
6(6), e831. Article e831.
https://doi.org/10.1038/tp.2016.99
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J.
, Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018).
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice.
Scientific Reports,
8(1), 16486. Article 16486.
https://doi.org/10.1038/s41598-018-34729-5
Paternoster, V., Svanborg, M., Edhager, A. V., Rajkumar, A. P., Eickhardt, E. A., Pallesen, J., Grove, J., Qvist, P., Fryland, T., Wegener, G., Nyengaard, J. R., Mors, O., Palmfeldt, J., Børglum, A. D. & Christensen, J. H. (2019).
Brain proteome changes in female Brd1+/- mice unmask dendritic spine pathology and show enrichment for schizophrenia risk.
Neurobiology of Disease,
124, 479-488.
https://doi.org/10.1016/j.nbd.2018.12.011
Starnawska, A., Tan, Q., Lenart, A., McGue, M.
, Mors, O., Børglum, A. D., Christensen, K.
, Nyegaard, M. & Christiansen, L. (2017).
Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins.
Neurobiology of Aging,
50, 60-63.
https://doi.org/10.1016/j.neurobiolaging.2016.10.025
Christensen, K. J.
, Dreier, J. W., Skotte, L., Feenstra, B.
, Grove, J., Børglum, A., Mitrovic, M., Cotsapas, C.
& Christensen, J. (2021).
Birth characteristics and risk of febrile seizures.
Acta Neurologica Scandinavica,
144(1), 51-57.
https://doi.org/10.1111/ane.13420
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., Del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J. ... Bipolar Disorder Working Group of the Psychiatric Genomics Consortium (2021).
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
Molecular Psychiatry,
26(4), 1286-1298.
https://doi.org/10.1038/s41380-019-0558-2
Gregersen, N., Buttenschøn, H. N., Nygaard, M.
, Kristensen, A. S., Woldbye, D., Joensen, S., Kruse, T. A.
, Børglum, A., Mors, O., Dahl, H. & Hedemand, A. (2009).
A PH sensitive sodium channel is a potential candidate gene for panic disorder. Poster session presented at World Congress of Psychiatric Genetics: Surfing the Wave of Discovery, San Diego, United States.
Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M.
, Lescai, F., Demontis, D., Kosmicki, J. A.
, Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., iPSYCH-Broad Consortium, Nordentoft, M.
, Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M. ... Daly, M. J. (2019).
Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants.
Nature Neuroscience,
22(12), 1961-1965.
https://doi.org/10.1038/s41593-019-0527-8
Demontis, D., Walters, R. K.
, Rajagopal, V. M., Waldman, I. D.
, Grove, J., Als, T. D., Dalsgaard, S., Ribasés, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M.
, Mors, O., Mortensen, P. B., ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Cormand, B., Hougaard, D. M., Neale, B. M., Franke, B.
... Børglum, A. D. (2021).
Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature communications (2021) 12 1 (576)).
Nature Communications,
12, Article 1166.
https://doi.org/10.1038/s41467-021-21566-w
Soler Artigas, M., Sánchez-Mora, C., Rovira, P., Richarte, V., Garcia-Martínez, I., Pagerols, M.
, Demontis, D., Stringer, S., Vink, J. M.
, Børglum, A. D., Neale, B. M., Franke, B., Faraone, S. V., Casas, M., Ramos-Quiroga, J. A., Ribasés, M., ADHD Group of the Psychiatric Genomics Consortium, International Cannabis Consortium & International Cannabis Consortium (2020).
Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality.
Molecular Psychiatry,
25(10), 2493-2503.
https://doi.org/10.1038/s41380-018-0339-3
Severinsen, J., Binderup, H.
, Mors, O., Wang, A. G., Vang, M., Murray, V., Muir, W., Mckee, I., Kruse, T. A., Blackwood, D. HR., Ewald, H.
& Børglum, A. (2002).
Association study of candidate genes for susceptibility to schizophrenia and bipolar disorder on chromosome 22Q13. Abstract from X World Congress on Psychiatric Genetics, 2002, Bruxelles, Belgium.
Nyegaard, M., Zacharov, T. F., Hedemand, A., Sørensen, K., Nordentoft, M., Nørgaard-Pedersen, B., Werge, T., Andersen, P., Hougaard, D. M.
, Pedersen, C. B., Mortensen, P. B., Mors, O. & Børglum, A. (2008).
Association study between the five subunits of the NMDA receptor (GRIN1, GRIN2A, GRIN2B, GRIN2C and GRIN2D genes) and schizophrenia in a large DAnish sample. Poster session presented at XVIth World Congress on Psychiatric Genetics, Osaka, Japan.
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J.
, Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, T. & Ingason, A. (2023).
Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study.
The Lancet Psychiatry,
10(2), 129-138.
https://doi.org/10.1016/S2215-0366(23)00004-4
Krebs, M. D., Themudo, G. E., Benros, M. E.
, Mors, O., Børglum, A. D., Hougaard, D.
, Mortensen, P. B., Nordentoft, M., Gandal, M. J., Fan, C. C., Geschwind, D. H., Schork, A. J., Werge, T. & Thompson, W. K. (2021).
Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors.
Nature Communications,
12(1), Article 6617.
https://doi.org/10.1038/s41467-021-26903-7
Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T.-K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research Team, McIntosh, A. M. & Whalley, H. C. (2019).
Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank.
Biological psychiatry. Cognitive neuroscience and neuroimaging,
4(1), 91-100.
https://doi.org/10.1016/j.bpsc.2018.07.006
Laursen, T. M., Trabjerg, B. B., Mors, O., Børglum, A. D., Hougaard, D. M.
, Mattheisen, M., Meier, S. M., Byrne, E. M.
, Mortensen, P. B., Munk-Olsen, T. & Agerbo, E. (2017).
Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study.
Schizophrenia Research,
184, 122-127.
https://doi.org/10.1016/j.schres.2016.12.001
Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O.
, Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, M.
, Børglum, A. D., Werge, T.
, Agerbo, E. & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium (2019).
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population.
JAMA Psychiatry,
76(5), 516-525.
https://doi.org/10.1001/jamapsychiatry.2018.4166
Demontis, D., Nyegaard, M., Buttenschøn, H. N., Hedemand, A., Pedersen, C. B., Grove, J., Flint, T. J., Nordentoft, M., Werge, T., Hougaard, D. M., Sørensen, K. M., Yolken, R. H.
, Mors, O., Børglum, A. D. & Mortensen, P. B. (2011).
Association of GRIN1 and GRIN2A-D With schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
156(8), 913-922.
https://doi.org/10.1002/ajmg.b.31234
Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T.
, Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M.
, Børglum, A. D., Mors, O. ... Pedersen, C. B. (2019).
Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia.
JAMA network open,
2(11), Article e1914401.
https://doi.org/10.1001/jamanetworkopen.2019.14401
Petersen, M., Andersen, J. T., Hjelvang, B. R., Broedbaek, K., Afzal, S.
, Nyegaard, M., Børglum, A. D., Stender, S., Køber, L. V., Torp-Pedersen, C. T. & Poulsen, H. E. (2011).
Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patients.
British Journal of Clinical Pharmacology,
71(4), 556-565.
https://doi.org/10.1111/j.1365-2125.2010.03868.x
Gregersen, N., Buttenschøn, H. N., Dahl, H. A.
, Foldager, L., Als, T. D., Wang, A., Joensen, S.
, Kristensen, A. S., Woldbye, D., Koefoed, P., Kruse, T. A.
, Børglum, A. & Mors, O. (2010).
Association mellem markører på kromosom 19p13 og panikangst. Poster session presented at Psykiatriens 5. Forskningsdag, Risskov, Denmark.
Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E.
, Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P.
, Debost, J. C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C.
, Laursen, T. M., Lim, C. C. W.
, Mors, O., Mortensen, P. B. ... McGrath, J. J. (2020).
Association between Mental Disorders and Subsequent Medical Conditions.
The New England Journal of Medicine,
382(18), 1721-1731.
https://doi.org/10.1056/NEJMoa1915784
Rietschel, M., Mattheisen, M., Degenhardt, F., Kahn, R. S., Linszen, D. H., Os, J. V., Wiersma, D., Bruggeman, R., Cahn, W., de Haan, L., Krabbendam, L., Myin-Germeys, I., Mühleisen, T. W., Kirsch, P., Esslinger, C., Herms, S.
, Demontis, D., Steffens, M., Strohmaier, J. ... Cichon, S. (2012).
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.
Molecular Psychiatry,
17(9), 906–917.
https://doi.org/10.1038/mp.2011.80
Backlund, L., Rosvall, L.
, Mors, O., Kockum, I., Traskman-Bendz, L., Frisén, L.
, Børglum, A., Mortensen, P., Isacsson, G., Agren, H., Schalling, M. & Osby, U. (2005).
Association between g72 haplotypes and bipolar disorder in a nordic sample. Abstract from Association between g72 haplotypes and bipolar disorder in a nordic sample.
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M.
, McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, M.
, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, T.
, Svenning, J.-C. & Horsdal, H. T. (2020).
Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia.
Schizophrenia Bulletin,
46(6), 1629-1637.
https://doi.org/10.1093/schbul/sbaa058
Severinsen, J., Als, T. D., Binderup, H., Wang, AG., Kruse, TA., Muir, WJ., Blackwood, DH.
, Mors, O. & Børglum, A. (2005).
Association analysis suggesting GPR24 as a shared susceptibility gene for bipolar affective disorder and schizophrenia. Abstract from XIII World Congress on Psychiatric Genetics 2005 Boston, USA.
Møller-Larsen, S., Nyegaard, M., Haagerup, A., Vestbo, J., Kruse, T.
& Børglum, A. (2008).
Association analysis identifies TLR7 and TLR8 as novel risk genes in asthma and related disorders.
Thorax,
63, 1064-9.
Severinsen, J., Als, T. D., Binderup, H., Kruse, T. A., Wang, A. G., Muir, W. J., Blackwood, D. H. R.
, Mors, O. & Børglum, A. (2006).
Association analyses suggest GPR24 as a shared susceptibility gene for bipolar affective disorder and schizophrenia.
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics,
141B, 524-533.
Børglum, A. D., Byskov, A., Ragno, P., Roldan, A. L., Tripputi, P., Cassani, G., Danø, K., Blasi, F.
, Bolund, L. & Kruse, T. A. (1992).
Assignment of the urokinase-type plasminogen activator receptor gene (PLAUR) to chromosome 19q13.1-q13.2.
American Journal of Human Genetics,
50(3), 492-7.
Børglum, A. D., Flint, T., Tommerup, N., Fleckner, J.
, Justesen, J. & Kruse, T. A. (1996).
Assignment of the human tryptophanyl-tRNA synthetase gene (WARS) to chromosome 14q32.2 --> q32.32.
Cytogenetic and Genome Research,
73(1-2), 99-103.
Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Schierup, M. H. & Danish Pan-Genome Consortium (Jakob Grove, member of -) (2017).
Assembly and analysis of 100 full MHC haplotypes from the Danish population.
Genome Research,
27(9), 1597-1607.
https://doi.org/10.1101/gr.218891.116
Deleuran, T.
, Olsen, I. M., Hansen, M. M.
, Zacharov, T. F., Børglum, A., Als, T. D. & Mors, O. (2008).
A significant association study of bipolar affective disorder on chrosome 12q24. Abstract from World Congress on Psychiatric Genetics XV, New York, United States.