Dinet, V., An, N., Ciccotosto, G. D., Bruban, J., Maoui, A., Bellingham, S. A., Hill, A. F.
, Andersen, O. M., Nykjaer, A., Jonet, L., Cappai, R. & Mascarelli, F. (2011).
APP involvement in retinogenesis of mice.
Acta Neuropathologica,
121(3), 351-63.
https://doi.org/10.1007/s00401-010-0762-2
Sørensen, M. V., Prætorius, H., Nykjær, A., Willnow, T.
& Leipziger, J. G. (2011).
Impaired aldosterone responsiveness in corticosteroid deficient mice. Acta Physiologica (Print),
201, 169-177.
Evans, S. F., Irmady, K., Ostrow, K., Kim, T.
, Nykjaer, A., Saftig, P., Blobel, C. & Hempstead, B. L. (2011).
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.
Journal of Biological Chemistry,
286(34), 29556-67.
https://doi.org/10.1074/jbc.M111.219675
Tauris, J., Gustafsen, C., Christensen, E. I., Jansen, P., Nykjaer, A., Nyengaard, J. R., Teng, K. K., Schwarz, E.
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Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons.
European Journal of Neuroscience,
33, 622-631.
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Klinger, S. C., Glerup, S., Raarup, M. K., Mari, MC.
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, Kjærgaard, M. M., Bakke, O.
, Nykjær, A., Olivecrona, G.
, Petersen, C. M. & Nielsen, MS. (2011).
SorLA regulates lipoprotein lipase activity by intracellular trafficking. Poster session presented at PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Denmark.
Klinger, S. C., Glerup, S., Raarup, M. K., Mari, MC.
, Nyegaard, M., Koster, G.
, Prabakaran, T., Nilsson, SK.
, Kjærgaard, M. M., Bakke, O.
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, Petersen, C. M. & Nielsen, MS. (2011).
SorLA regulates lipoprotein lipase activity by intracellular trafficking. Abstract from PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Denmark.
Klinger, S. C., Glerup, S., Raarup, M. K., Mari, M. C.
, Nyegaard, M., Koster, G.
, Prabakaran, T., Nilsson, B. S.
, Kjaergaard, M. M., Bakke, O.
, Nykjær, A., Olivecrona, G.
, Petersen, C. M. & Nielsen, M. S. (2011).
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Journal of Cell Science,
124(Pt 7), 1095-105.
https://doi.org/10.1242/jcs.072538
Vaegter, C. B., Jansen, P., Fjorback, A. W., Glerup, S., Skeldal, S.
, Kjølby, M. F., Richner, M., Erdmann, B.
, Nyengaard, J. R., Tessarollo, L., Lewin, G. R., Willnow, T. E., Chao, M. V.
& Nykjaer, A. (2011).
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.
Nature Neuroscience,
14(1), 54-61.
https://doi.org/10.1038/nn.2689
Wähe, A., Kasmapour, B., Schmaderer, C., Liebl, D., Sandhoff, K.
, Nykjaer, A., Griffiths, G. & Gutierrez, M. G. (2010).
Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin.
Journal of Cell Science,
123(Pt 14), 2502-11.
https://doi.org/10.1242/jcs.067686
Andersen, O. S., Boisguerin, P.
, Glerup, S., Skeldal, S., Volkmer, R., Wilnow, T. E.
, Nykjær, A. & Andersen, O. M. (2010).
Identification of a linear epitope in sortilin that partakes in pro-neurotropin binding.
Journal of Biological Chemistry, 12210-12222.
Vardya, I., Holm, M. M., Dósa, Z., Nieto-Gonzalez, J. L., Nykjær, A. & Jensen, K. (2010).
Increased synaptic GABAergic inhibition in dentate gyrus of mice deficient of sortilin. Joint meeting of the Scandinavian and German Physiological Societies Mar. 27 2010 - Mar. 30 2010 Copenhagen, Denmark. Poster session presented at Joint meeting of the Scandinavian and German physiological societies, Copenhagen, Denmark.
Reiche, J., Theilig, F., Rafiqi, F. H., Militz, D., Mutig, K., Todiras, M.
, Christensen, E. I., Ellison, D. H., Bader, M.
, Nykjaer, A., Bachmann, S., Alessi, D. & Willnow, T. E. (2010).
SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2.
Molecular and Cellular Biology,
30, 3027-3037.
https://doi.org/10.1128/MCB.01560-09
Kjølby, M. F., Andersen, O. M., Breiderhoff, T.
, Fjorback, A. N., Pedersen, K.-M., Madsen, P. S., Jansen, P., Heeren, J., Willnow, T.
& Nykjær, A. (2010).
Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metabolism,
12(3), 213-223.
Hu, F., Padukkavidana, T.
, Vægter, C. B., Brady, O., Zheng, Y., Mackenzie, I., Feldman, H.
, Nykjær, A. & Strittmatter, S. (2010).
Sortilin-Mediated Endocytosis Determines Levels of the Fronto-Temporal Dementia Protein, Progranulin.
Neuron,
68(4), 654-667.
Tauris, J., Christensen, E. I., Nykjær, A., Jacobsen, C., Petersen, C. M. & Ovesen, T. (2009).
Cubilin and Megalin Co-Localize in the Neonatal Inner Ear.
Audiology and Neuro-Otology,
14(4), 267-278.
https://doi.org/10.1159/000199446
Holm, M. M., Nieto-Gonzales, J. L., Vardya, I., Vægter, C. B., Nykjær, A. & Jensen, K. (2009).
Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus.
Journal of Neuroscience,
29(40), 12412-8.
Gustafsen, C., Tauris, J., Christensen, E. I., Jansen, P., Nykjær, A., Teng, K. K., Schwarz, E.
, Madsen, P. S. & Petersen, C. M. (2009).
The neurotrophin precursor proNT-3 promotes Sortilin:p75NTR complex formation and induces apoptosis. Poster session presented at Society for Neuroscience 2009, Chicago, United States.
Vægter, C. B., Jansen, P., Erdmann, B., WillNow, T., Lewin, G., Tessarollo, L.
& Nykjær, A. (2008).
Sortilin positively modulates survival signaling by mature neurotrophins. Poster session presented at Society for Neuroscience 38th Annual Meeting, Washington, United States.
Kjærgaard, M., Skeldal, S.
, Raarup, M. K., Nykjær, A., Nyengaard, J. R. & Nielsen, M. S. (2008).
Using FRET in the study of the Vps10pD receptors: Annual Meeting of the Nordic Microscopy Society (Scandem).
Jansen, P., Giehl, K., Nyengaard, J. R., Teng, K., Lioubinski, O.
, Sjoegaard, S. S., Breiderhoff, T., Gotthardt, M.
, Lin, F., Eilers, A.
, Petersen, C. M., Lewin, G. R., Hempstead, B. L., Willnow, T. E.
& Nykjaer, A. (2007).
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nature Neuroscience,
10(11), 1449-57.
https://doi.org/10.1038/nn2000
Hermey, G., Sjøgaard, S., Petersen, C. M., Nykjær, A. & Gliemann, J. (2006).
Tumour necrosis factor-α convertase mediates ectodomain shedding of Vps10p-domain receptor family members.
Biochemical Journal,
395(2), 285-293.
Andersen, O. M., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., von Arnim, C. A., Breiderhoff, T.
, Jansen, P., Wu, X., Bales, K. R., Cappai, R., Masters, C. L.
, Gliemann, J., Mufson, E. J., Hyman, B. T., Paul, S. M.
, Nykjær, A. & Willnow, T. E. (2005).
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Proceedings of the National Academy of Sciences (PNAS),
102(38), 13461-13466.
Teng, H. K., Teng, K. K., Lee, R., Wright, S., Tevar, S., Almeida, R. D., Kermani, P., Torkin, R., Chen, Z. Y., Lee, F. S., Kraemer, R. T.
, Nykjær, A. & Hempstead, B. L. (2005).
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.
Journal of Neuroscience,
25, 5455-5463.
Hammes, A.
, Andreassen, T. K., Spoelgen, R., Raila, J., Huebner, N., Schulz, H., Metzger, J., Schweigert, F. J., Luppa, P. B.
, Nykjær, A. & Willnow, T. E. (2005).
Role of endocytosis in cellular uptake of sex steroids.
Cell,
122, 751-762.
Chen, Z. Y., Ieraci, A., Teng, H. K., Dall, H., Meng, C. X., Herrera, D. G.
, Nykjær, A., Hempstead, B. L. & Lee, F. S. (2005).
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.
Journal of Neuroscience,
25, 6155-6166.
Westergaard, U. B.
, Sørensen, E. S., Hermey, G.
, Nielsen, M. S., Nykjær, A., Kirkegaard, K., Jacobsen, C., Gliemann, J., Madsen, P. S. & Pedersen, J. C. M. (2004).
Functional organization of the sortilin Vps10p domain.
Journal of Biological Chemistry,
279, 50221-50229.
Nykjær, A., Lee, R., Teng, K. K.
, Jansen, P., Madsen, P. S., Nielsen, M. S., Jacobsen, C., Kliemannel, M., Schwarz, E., Willnow, T. E., Hempstead, B. L.
& Pedersen, J. C. M. (2004).
Sortilin is essential for proNGF-induced neuronal cell death.
Nature,
427, 843-848.
Gliemann, J., Hermey, G.
, Nykjær, A., Petersen, C. M., Jacobsen, C.
& Andreasen, P. (2004).
The mosaic receptor sorLA/LR11 binds components of the plasminogen activating system and PDGF-BB similarity to low density lipoprotein receptor-related protein (LRP1) but mediates slow internalization of bound.
Biochemical Journal,
381, 203-212.
Gliemann, J., Hermey, G.
, Nykjær, A., Pedersen, J. C. M., Jacobsen, C. & Andreasen, P. A. (2004).
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand. Biochemical Journal,
381, 203-212.
Leheste, J. R., Melsen, F., Wellner, M.
, Jansen, P., Schlichting, U., Renner-Muller, I., Andreassen, T. T., Wolf, E., Bachmann, S.
, Nykjær, A. & Willnow, T. E. (2003).
Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect.
The FASEB Journal, (17), 247-249.