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Evans, S. F., Irmady, K., Ostrow, K., Kim, T., Nykjaer, A., Saftig, P., Blobel, C. & Hempstead, B. L. (2011). Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. Journal of Biological Chemistry, 286(34), 29556-67. https://doi.org/10.1074/jbc.M111.219675

Tauris, J., Gustafsen, C., Christensen, E. I., Jansen, P., Nykjaer, A., Nyengaard, J. R., Teng, K. K., Schwarz, E., Ovesen, T., Madsen, P. & Petersen, C. M. (2011). Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons. European Journal of Neuroscience, 33, 622-631. https://doi.org/10.1111/j.1460-9568.2010.07556.x

Skeldal, S., Matusica, D., Nykjaer, A. & Coulson, E. J. (2011). Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: Neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75(NTR). BioEssays, 33(8), 614-25. https://doi.org/10.1002/bies.201100036

Klinger, S. C., Glerup, S., Raarup, M. K., Mari, MC., Nyegaard, M., Koster, G., Prabakaran, T., Nilsson, SK., Kjærgaard, M. M., Bakke, O., Nykjær, A., Olivecrona, G., Petersen, C. M. & Nielsen, MS. (2011). SorLA regulates lipoprotein lipase activity by intracellular trafficking. Poster session presented at PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Denmark.

Klinger, S. C., Glerup, S., Raarup, M. K., Mari, MC., Nyegaard, M., Koster, G., Prabakaran, T., Nilsson, SK., Kjærgaard, M. M., Bakke, O., Nykjær, A., Olivecrona, G., Petersen, C. M. & Nielsen, MS. (2011). SorLA regulates lipoprotein lipase activity by intracellular trafficking. Abstract from PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Denmark.

Klinger, S. C., Glerup, S., Raarup, M. K., Mari, M. C., Nyegaard, M., Koster, G., Prabakaran, T., Nilsson, B. S., Kjaergaard, M. M., Bakke, O., Nykjær, A., Olivecrona, G., Petersen, C. M. & Nielsen, M. S. (2011). SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. Journal of Cell Science, 124(Pt 7), 1095-105. https://doi.org/10.1242/jcs.072538

Vaegter, C. B., Jansen, P., Fjorback, A. W., Glerup, S., Skeldal, S., Kjølby, M. F., Richner, M., Erdmann, B., Nyengaard, J. R., Tessarollo, L., Lewin, G. R., Willnow, T. E., Chao, M. V. & Nykjaer, A. (2011). Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nature Neuroscience, 14(1), 54-61. https://doi.org/10.1038/nn.2689

Kjølby, M. F. (2011). Sortilins in cardiovascular disease and diabetes. Århus Universitet.

Willnow, T., Kjølby, M. F. & Nykjær, A. (2011). Sortilins: new players in lipoprotein metabolism. Current Opinion in Lipidology, 22(2), 79-85. https://doi.org/10.1097/MOL.0b013e3283416f2b

Richner, M., Bjerrum, O. J., Nykjær, A. & Vægter, C. B. (2011). The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice. Journal of Visualized Experiments, 54. http://www.jove.com/details.php?id=3092

Willnow, T. E. & Nykjaer, A. (2010). Cellular uptake of steroid carrier proteins--mechanisms and implications. Molecular and Cellular Endocrinology, 316(1), 93-102. https://doi.org/10.1016/j.mce.2009.07.021

Kjølby, M. F. (2010). Det store lotteri. Weekendavisen.

Wähe, A., Kasmapour, B., Schmaderer, C., Liebl, D., Sandhoff, K., Nykjaer, A., Griffiths, G. & Gutierrez, M. G. (2010). Golgi-to-phagosome transport of acid sphingomyelinase and prosaposin is mediated by sortilin. Journal of Cell Science, 123(Pt 14), 2502-11. https://doi.org/10.1242/jcs.067686

Andersen, O. S., Boisguerin, P., Glerup, S., Skeldal, S., Volkmer, R., Wilnow, T. E., Nykjær, A. & Andersen, O. M. (2010). Identification of a linear epitope in sortilin that partakes in pro-neurotropin binding. Journal of Biological Chemistry, 12210-12222.

Vardya, I., Holm, M. M., Dósa, Z., Nieto-Gonzalez, J. L., Nykjær, A. & Jensen, K. (2010). Increased synaptic GABAergic inhibition in dentate gyrus of mice deficient of sortilin. Joint meeting of the Scandinavian and German Physiological Societies Mar. 27 2010 - Mar. 30 2010 Copenhagen, Denmark. Poster session presented at Joint meeting of the Scandinavian and German physiological societies, Copenhagen, Denmark.

Mufson, E. J., Wuu, J., Counts, S. E. & Nykjaer, A. (2010). Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease. Neuroscience Letters, 471(3), 129-33. https://doi.org/10.1016/j.neulet.2010.01.023

Reiche, J., Theilig, F., Rafiqi, F. H., Militz, D., Mutig, K., Todiras, M., Christensen, E. I., Ellison, D. H., Bader, M., Nykjaer, A., Bachmann, S., Alessi, D. & Willnow, T. E. (2010). SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2. Molecular and Cellular Biology, 30, 3027-3037. https://doi.org/10.1128/MCB.01560-09

Kjølby, M. F., Andersen, O. M., Breiderhoff, T., Fjorback, A. N., Pedersen, K.-M., Madsen, P. S., Jansen, P., Heeren, J., Willnow, T. & Nykjær, A. (2010). Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. Cell Metabolism, 12(3), 213-223.

Hu, F., Padukkavidana, T., Vægter, C. B., Brady, O., Zheng, Y., Mackenzie, I., Feldman, H., Nykjær, A. & Strittmatter, S. (2010). Sortilin-Mediated Endocytosis Determines Levels of the Fronto-Temporal Dementia Protein, Progranulin. Neuron, 68(4), 654-667.

Nykjaer, A., Schambye, H., Pedersen, A. H. & Nielsen, H. (2009). Assessing low-dose gentamicin-induced kidney injury in rats by analysis of urine. Journal of Pharmacological and Toxicological Methods, 60(3), 316-20. https://doi.org/10.1016/j.vascn.2009.07.006

Tauris, J., Christensen, E. I., Nykjær, A., Jacobsen, C., Petersen, C. M. & Ovesen, T. (2009). Cubilin and Megalin Co-Localize in the Neonatal Inner Ear. Audiology and Neuro-Otology, 14(4), 267-278. https://doi.org/10.1159/000199446

Skeldal, S. (2009). Functional interactions between the Vps10p domain receptor family and their co-receptors.

Dolatshahi-Pirouz, A., Skeldal, S., Hovgaard, M. B., Jensen, T. H. L., Foss, M., Chevallier, J. & Besenbacher, F. (2009). Influence of nano-roughness and the detailed surface morphology on the structural properties and water coupling capabilities of surface bound fibrinogen films. Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, 113(11), 4406.

Holm, M. M., Nieto-Gonzales, J. L., Vardya, I., Vægter, C. B., Nykjær, A. & Jensen, K. (2009). Mature BDNF, but not proBDNF, reduces excitability of fast-spiking interneurons in mouse dentate gyrus. Journal of Neuroscience, 29(40), 12412-8.

Dolatshahi-Pirouz, A., Pennisi, C. P., Skeldal, S., Foss, M., Chevallier, J., Zachar, V., Andreasen, P., Yoshida, K. & Besenbacher, F. (2009). The Influence of glancing angle deposited (GLAD) nano-rough platinum surfaces on the adsorption of fibrinogen and the proliferation of primary human fibroblasts. Nanotechnology, 20, 095101. https://doi.org/10.1088/0957-4484/20/9/095101

Gustafsen, C., Tauris, J., Christensen, E. I., Jansen, P., Nykjær, A., Teng, K. K., Schwarz, E., Madsen, P. S. & Petersen, C. M. (2009). The neurotrophin precursor proNT-3 promotes Sortilin:p75^NTR complex formation and induces apoptosis. Poster session presented at Society for Neuroscience 2009, Chicago, United States.

Nykjær, A. & Kjølby, M. F. (2009). (WO/2009/140972) MODULATION OF THE VPS10P-DOMAIN RECEPTORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE. (Patent No. PCT/DK2009/050115).

Kjølby, M. F. & Bie, P. (2008). Chronic activation of plasma renin is log-linearly related to dietary sodium and eliminates natriuresis in response to a pulse change in total body sodium. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 294(1), r17-25.

Willnow, T. E., Hammes, A. & Nykjær, A. (2008). Endocytosis of sex stereoids: The hypothesis of free hormones revisited. Annales d'Endocrinologie, 69, 101-2.

Dolatshahi-Pirouz, A., Pennisi, C. P. A., Skeldal, S., Foss, M., Chevallier, J., Kingshott, P., Zachar, V., Yoshida, K. & Besenbacher, F. (2008). Nano-rough surfaces produced by glancing angle deposition for protein adsorption measurements and cellular assays. Abstract from American Vacuum Society, annual meeting 2008, Boston, United States.

Vægter, C. B., Jansen, P., Erdmann, B., WillNow, T., Lewin, G., Tessarollo, L. & Nykjær, A. (2008). Sortilin positively modulates survival signaling by mature neurotrophins. Poster session presented at Society for Neuroscience 38th Annual Meeting, Washington, United States.

Kjærgaard, M., Skeldal, S., Raarup, M. K., Nykjær, A., Nyengaard, J. R. & Nielsen, M. S. (2008). Using FRET in the study of the Vps10pD receptors: Annual Meeting of the Nordic Microscopy Society (Scandem).

Willnow, T. E., Petersen, C. M. & Nykjær, A. (2008). VPs10p-domain receptors . central regulators of neuronal viability. Nature Reviews. Neuroscience, 9, 899-909.

Jansen, P., Giehl, K., Nyengaard, J. R., Teng, K., Lioubinski, O., Sjoegaard, S. S., Breiderhoff, T., Gotthardt, M., Lin, F., Eilers, A., Petersen, C. M., Lewin, G. R., Hempstead, B. L., Willnow, T. E. & Nykjaer, A. (2007). Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nature Neuroscience, 10(11), 1449-57. https://doi.org/10.1038/nn2000

Skeldal, S., Larsen, J. V., Pedersen, K. E., Petersen, H. H., Egelund, R., Christensen, A., Jensen, J. K., Gliemann, J. & Andreasen, P. (2006). Binding areas of Urokinase-type plasminogen activator inhibitor-1 complex for endocytosis receptors of the low density lipoprotein receptor family, determined by site-directed mutagenesis. Poster session presented at Annual Meeting of the " Cancer Degradome", København, Denmark.

Skeldal, S., Larsen, J. V., Pedersen, K. E., Petersen, H. H., Egelund, R., Christensen, A., Jensen, J. K., Gliemann, J. & Andreasen, P. (2006). Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low density lipoprotein receptor family, determined by site-directed mutagenesis. FEBS journal, 273, 5143-5159.

Skeldal, S., Larsen, J. V., Pedersen, K. E., Petersen, H. H., Egelund, R., Christensen, A., Jensen, J. K., Gliemann, J. & Andreasen, P. A. (2006). Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis. FEBS journal, 273(22), 5143-59. https://doi.org/10.1111/j.1742-4658.2006.05511.x

Kjølby, M. F., Müller, K. & Schumacher, M. (2006). Cerebellopontine angle primary diffuse large B cell (non-Hodgkins) lymphoma mimicking an acoustic schwannoma. European Journal of Radiology Extra, 60(3), 93-96.

Jensen, J. K., Malmendal, A., Schiøtt, B., Skeldal, S., Pedersen, K. E., Celik, L., Nielsen, N. C., Andreasen, P. & Wind, T. (2006). Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low density lipoprotein receptor family by a peptide isolated from a phage displayed library. Biochem. J., 399, 387-396.

Jensen, J. K., Malmendal, A., Schiøtt, B., Skeldal, S., Pedersen, K. E., Celik, L., Nielsen, N. C., Andreasen, P. A. & Wind, T. (2006). Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library. Biochemical Journal, 399(3), 387-96. https://doi.org/10.1042/BJ20060533

Dupont, D. M., Hansen, M., Jensen, J. K., Kristiansen, S. K., Mathiasen, L., Pedersen, K. E., Skeldal, S., Wind, T., Malmendal, A., Schiøtt, B., Nielsen, N. C. & Andreasen, P. (2006). Novel conformational probes and activity regulators of plasminogen avtivator inhibitor-1, isolated from phage-displayed disulfide bridge constrained peptide libraries. Poster session presented at Annual Meeting of the "Cancer Degradome", København, Denmark.

Willnow, T. E. & Nykjær, A. (2006). Response: cellular uptake of ex steroid hormones. Cell, 124, 456-457.

Hermey, G., Sjøgaard, S., Petersen, C. M., Nykjær, A. & Gliemann, J. (2006). Tumour necrosis factor-alpha convertase mediates ectodomain shedding of Vps10p-domain receptor family members. Biochem. J.

Hermey, G., Sjøgaard, S., Petersen, C. M., Nykjær, A. & Gliemann, J. (2006). Tumour necrosis factor-α convertase mediates ectodomain shedding of Vps10p-domain receptor family members. Biochem. J., 395(2), 285-293.

Kjølby, M. F., Kompanowska-Jezierska, E., Wamberg, S. & Bie, P. (2005). Effects of sodium intake on plasma potassium and renin angiotensin aldosterone system in conscious dogs. Acta Physiologica (Print), 184(3), 225-234.

Andersen, O. M., Reiche, J., Schmidt, V., Gotthardt, M., Spoelgen, R., Behlke, J., von Arnim, C. A., Breiderhoff, T., Jansen, P., Wu, X., Bales, K. R., Cappai, R., Masters, C. L., Gliemann, J., Mufson, E. J., Hyman, B. T., Paul, S. M., Nykjær, A. & Willnow, T. E. (2005). Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proceedings of the National Academy of Sciences (PNAS), 102(38), 13461-13466.

Nykjær, A., Willnow, T. E. & Pedersen, J. C. M. (2005). p75^NTR – To live or let die. Curr. Opin. Neurobiol., 15, 49-57.

Teng, H. K., Teng, K. K., Lee, R., Wright, S., Tevar, S., Almeida, R. D., Kermani, P., Torkin, R., Chen, Z. Y., Lee, F. S., Kraemer, R. T., Nykjær, A. & Hempstead, B. L. (2005). ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75^NTR and sortilin. Journal of Neuroscience, 25, 5455-5463.

Hammes, A., Andreassen, T. K., Spoelgen, R., Raila, J., Huebner, N., Schulz, H., Metzger, J., Schweigert, F. J., Luppa, P. B., Nykjær, A. & Willnow, T. E. (2005). Role of endocytosis in cellular uptake of sex steroids. Cell, 122, 751-762.

Chen, Z. Y., Ieraci, A., Teng, H. K., Dall, H., Meng, C. X., Herrera, D. G., Nykjær, A., Hempstead, B. L. & Lee, F. S. (2005). Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. Journal of Neuroscience, 25, 6155-6166.

Displaying results 101 to 150 out of 178

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Susanne Schousboe Sjøgaard