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Hu, F., Padukkavidana, T., Vægter, C. B., Brady, O., Zheng, Y., Mackenzie, I., Feldman, H., Nykjær, A. & Strittmatter, S. (2010). Sortilin-Mediated Endocytosis Determines Levels of the Fronto-Temporal Dementia Protein, Progranulin. Neuron, 68(4), 654-667.
Hoffmann, M., Hofmann-Winkler, H., Smith, J. C., Krüger, N., Arora, P., Sørensen, L. K., Søgaard, O. S., Hasselstrøm, J. B., Winkler, M., Hempel, T., Raich, L., Olsson, S., Danov, O., Jonigk, D., Yamazoe, T., Yamatsuta, K., Mizuno, H., Ludwig, S., Noé, F. ... Pöhlmann, S. (2021). Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65, Article 103255. https://doi.org/10.1016/j.ebiom.2021.103255
Hilpert, J., Vorum, H., Burmeister, R., Spoelgen, R., Grishkovskaya, I., Misselwitz, R., Nykjær, A. & Willnow, T. E. (2001). Efficient eukaryotic expression system for authentic human sex hormone-binding globulin. Biochemical Journal, 360, 609-615.
Hilpert, J., Wogensen, L., Thykjaer, T., Wellner, M., Schlichting, U., Ørntoft, T. F., Bachmann, S., Nykjær, A. & Willnow, T. E. (2002). Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney International, 62(5), 1672-1681.
Hammes, A., Andreassen, T. K., Spoelgen, R., Raila, J., Huebner, N., Schulz, H., Metzger, J., Schweigert, F. J., Luppa, P. B., Nykjær, A. & Willnow, T. E. (2005). Role of endocytosis in cellular uptake of sex steroids. Cell, 122, 751-762.
Graae, A.-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjolby, M., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A. ... Holst, B. (2019). ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations. Diabetes, 68(3), 502-514. https://doi.org/10.2337/db18-0418
Gould, E., Fraser, H. S., Parker, T. H., Nakagawa, S., Griffith, S. C., Vesk, P. A., Fidler, F., Hamilton, D. G., Abbey-Lee, R. N., Abbott, J. K., Aguirre, L. A., Alcaraz, C., Aloni, I., Altschul, D., Arekar, K., Atkins, J. W., Atkinson, J., Baker, C. M., Barrett, M. ... Zitomer, R. A. (2025). Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology. BMC Biology, 23(1), Article 35. https://doi.org/10.1186/s12915-024-02101-x
Goettsch, C., Hutscheson, JD., Aikawa, M., Iwata, H., Pham, T., Nykjær, A., Kjølby, M. F., Rogers, M., Michel, T., Shibasaki, M., Hagita, S., Kramann, R., Rader, D. J., Libby, P., Singh, SA. & Aikawa, E. (2016). Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. Journal of Clinical Investigation, 126(4), 1323-1336. https://doi.org/10.1172/JCI80851
Goettsch, C., Hutscheson, JD., Hagita, S., Rogers, M., Creager, MD., Pham, T., Choi, J., Mlynarchik, AK., Pieper, B., Kjølby, M. F., Aikawa, M. & Aikawa, E. (2016). A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis, 251, 109-118. https://doi.org/10.1016/j.atherosclerosis.2016.06.011
Goettsch, C., Kjølby, M. F. & Aikawa, E. (2018). Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(1), 19-25. https://doi.org/10.1161/ATVBAHA.117.310292
Gass, J., Lee, W. C., Cook, C., Finch, N., Stetler, C., Jansen-West, K., Lewis, J., Link, C. D., Rademakers, R., Nykjær, A. & Petrucelli, L. (2012). Progranulin regulates neuronal outgrowth independent of Sortilin. Molecular Neurodegeneration, 7, 33. https://doi.org/10.1186/1750-1326-7-33
Evans, S. F., Irmady, K., Ostrow, K., Kim, T., Nykjaer, A., Saftig, P., Blobel, C. & Hempstead, B. L. (2011). Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. Journal of Biological Chemistry, 286(34), 29556-67. https://doi.org/10.1074/jbc.M111.219675
Dinet, V., An, N., Ciccotosto, G. D., Bruban, J., Maoui, A., Bellingham, S. A., Hill, A. F., Andersen, O. M., Nykjaer, A., Jonet, L., Cappai, R. & Mascarelli, F. (2011). APP involvement in retinogenesis of mice. Acta Neuropathologica, 121(3), 351-63. https://doi.org/10.1007/s00401-010-0762-2
Chen, Z. Y., Ieraci, A., Teng, H. K., Dall, H., Meng, C. X., Herrera, D. G., Nykjær, A., Hempstead, B. L. & Lee, F. S. (2005). Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. Journal of Neuroscience, 25, 6155-6166.