Klinger, S. C., Højland, A., Jain, S.
, Kjolby, M., Madsen, P., Svendsen, A. D., Olivecrona, G., Bonifacino, J. S.
& Nielsen, M. S. (2016).
Polarized Trafficking of the Sorting Receptor SorLA in Neurons and MDCK Cells.
FEBS journal,
283(13), 2476–2493.
https://doi.org/10.1111/febs.13758
Hersom, M., Helms, H. C., Pretzer, N., Goldeman, C., Jensen, A. I., Severin, G.
, Nielsen, M. S., Holm, R. & Brodin, B. (2016).
Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers.
Molecular and Cellular Neuroscience,
76, 59-67.
https://doi.org/10.1016/j.mcn.2016.08.009Nyegaard, M., Rendtorff, N. D.
, Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., Hedemand, A., Buniello, A., Niola, F., Overgaard, M. T., Leal, S. M., Ahmad, W.
, Wikman, F. P., Petersen, K. B., Crüger, D. G., Oostrik, J., Kremer, H., Tommerup, N., Frödin, M.
... Børglum, A. D. (2015).
A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.
PLoS Genetics,
11(7), e1005386.
https://doi.org/10.1371/journal.pgen.1005386
Burkhart, A., Skjørringe, T., Johnsen, K. B.
, Siupka, P., Thomsen, L. B.
, Nielsen, M. S., Thomsen, L. L. & Moos, T. (2015).
Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier.
Molecular Neurobiology.
https://doi.org/10.1007/s12035-015-9582-7Carlo, A.-S.
, Gustafsen, C., Mastrobuoni, G.
, Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M.
, Nykjaer, A., Herz, J., Heeren, J., Kempa, S.
, Petersen, C. M. & Willnow, T. E. (2013).
The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain.
Journal of Neuroscience,
33(1), 358-70.
https://doi.org/10.1523/JNEUROSCI.2425-12.2013Progida, C.
, Nielsen, M. S., Koster, G., Bucci, C. & Bakke, O. (2012).
Dynamics of Rab7b-dependent transport of sorting receptors.
Traffic,
13(9), 1273–1285.
https://doi.org/10.1111/j.1600-0854.2012.01388.xKlinger, S. C., Højland, A., Gustafsen, C., Glerup, S., Kjølby, M. F., Helms, H. C.
, Raarup, M. K., Olivecrona, G., Brodin, B.
, Petersen, C. M., Nykjær, A. & Nielsen, M. S. (2012).
SorLA regulates trafficking of Lipoprotein Lipase in polarized cells and astrocytes. Poster session presented at Barriers of the CNS, New London NH, United States.
Gottfredsen, R. H., Tran, S. M.-H.
, Larsen, U. G., Madsen, P., Nielsen, M. S., Enghild, J. J. & Petersen, S. V. (2012).
The C-terminal proteolytic processing of extracellular superoxide dismutase is redox regulated.
Free Radical Biology & Medicine,
52(1), 191-197.
https://doi.org/10.1016/j.freeradbiomed.2011.10.443
Klinger, S. C., Glerup, S., Raarup, M. K., Mari, M. C.
, Nyegaard, M., Koster, G.
, Prabakaran, T., Nilsson, B. S.
, Kjaergaard, M. M., Bakke, O.
, Nykjær, A., Olivecrona, G.
, Petersen, C. M. & Nielsen, M. S. (2011).
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Journal of Cell Science,
124(Pt 7), 1095-105.
https://doi.org/10.1242/jcs.072538
Larsen, J. V., Hansen, M., Møller, B. K., Madsen, P. S., Scheller, J.
, Nielsen, M. S. & Petersen, C. M. (2010).
Sortilin Facilitates Signaling of Ciliary Neurotrophic Factor and Related Helical Type 1 Cytokines Targeting the gp130/Leukemia Inhibitory Factor Receptor β Heteromer.
Molecular and Cellular Biology,
30(17), 4175-4187.
Petersen, S. V., Thøgersen, I., Valnickova, Z., Nielsen, M. S., Petersen, J. S., Poulsen, E. T., Jacobsen, C., Oury, T. D.
, Moestrup, S. K., Crapo, J. D.
, Nielsen, N. C., Kristensen, T. & Enghild, J. J. (2010).
The concentration of extracellular superoxide dismutase in plasma is maintained by LRP-mediated endocytosis.
Free Radical Biology & Medicine,
49(5), 894-9.
https://doi.org/10.1016/j.freeradbiomed.2010.06.019
Nilsson, S. K.
, Christensen, S., Raarup, M. K., Ryan, R. O.
, Nielsen, M. S. & Olivecrona, G. (2008).
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.
Journal of Biological Chemistry,
283(38), 25920-7.
https://doi.org/10.1074/jbc.M802721200Kjærgaard, M., Skeldal, S.
, Raarup, M. K., Nykjær, A., Nyengaard, J. R. & Nielsen, M. S. (2008).
Using FRET in the study of the Vps10pD receptors: Annual Meeting of the Nordic Microscopy Society (Scandem).
Nielsen, M. S., Gustafsen, C., Madsen, P., Nyengaard, J. R., Hermey, G., Bakke, O., Mari, M., Schu, P., Pohlmann, R., Dennes, A.
& Petersen, C. M. (2007).
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. Molecular and Cellular Biology,
27(19), 6842-51.
https://doi.org/10.1128/MCB.00815-07
Gustafsen, C., Nielsen, M. S., Madsen, P. S., Dennes, A., Schu, P.
& Petersen, C. M. (2006).
The APP binding receptor SorLA mediates Golgi-endosome shuttling. Poster session presented at EMBO research conference on Interface of Cell Biology and Cellular Microbiology. Macromolecular Complexes in Microbial Pathogenesis, Membrane Trafficking and Cell Signalling, San Feliu de Guixols, Spain.
Westergaard, U. B.
, Kirkegaard, K., Sørensen, E. S., Jacobsen, C., Nielsen, M. S., Pedersen, J. C. M. & Madsen, P. S. (2005).
SorCS3 does not require propeptide cleavage to bind nerve growth factor.
FEBS Letters,
579(5), 1172-1176.
Westergaard, U. B.
, Sørensen, E. S., Hermey, G.
, Nielsen, M. S., Nykjær, A., Kirkegaard, K., Jacobsen, C., Gliemann, J., Madsen, P. S. & Pedersen, J. C. M. (2004).
Functional organization of the sortilin Vps10p domain.
Journal of Biological Chemistry,
279, 50221-50229.
Nykjær, A., Lee, R., Teng, K. K.
, Jansen, P., Madsen, P. S., Nielsen, M. S., Jacobsen, C., Kliemannel, M., Schwarz, E., Willnow, T. E., Hempstead, B. L.
& Pedersen, J. C. M. (2004).
Sortilin is essential for proNGF-induced neuronal cell death.
Nature,
427, 843-848.
Sarret, P., Krzykowski, P., Segal, L.
, Nielsen, M. S., Pedersen, J. C. M., Mazella, J., Stroh, T. & Beaudet, A. (2003).
Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system.
J. Comp. Neurol., (461), 483-505.
Kahns, S., Lykkebo, S., Jakobsen, L. D.
, Nielsen, M. S. & Jensen, P. H. (2002).
Caspase-mediated parkin cleavage in apoptotic cell death.
Journal of Biological Chemistry,
277, 15303-15308.
Jacobsen, L.
, Madsen, P. S., Nielsen, M. S., Geraerts, W. P. M.
, Gliemann, J., Smit, A. B.
& Pedersen, J. C. M. (2002).
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding.
FEBS Letters,
511(1-3), 155-158.
Dennes, A.
, Madsen, P. S., Nielsen, M. S., Pedersen, J. C. M. & Pohlmann, R. (2002).
The Yeast Vps10p Cytoplasmic Tail Mediates Lysosomal Sorting in Mammalian Cells and Interacts with Human GGAs.
Journal of Biological Chemistry,
277(14), 12288-12293.
Jacobsen, L.
, Madsen, P., Jacobsen, C., Nielsen, M. S., Gliemann, J. & Petersen, C. M. (2001).
Activation and functional characterization of the mosaic receptor SorLA/LR11.
Journal of Biological Chemistry,
276, 22788-22796.
Nykjær, A., Fyfe, J. C., Kozyraki, R., Leheste, J. R.
, Jacobsen, C., Nielsen, M. S., Verroust, P. J., Aminoff, M., de la Chapelle, A.
, Moestrup, S. K., Ray, R.
, Gliemann, J., Willnow, T. E.
& Christensen, E. I. (2001).
Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).
Proceedings of the National Academy of Sciences (PNAS),
98, 13895-13900.
Navarro, V., Martin, S., Sarret, P.
, Nielsen, M. S., Pedersen, J. C. M., Vincent, J.-P. & Mazella, J. (2001).
Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin.
FEBS Letters,
495, 100-105.
Nielsen, M. S., Madsen, P. S., Christensen, E. I., Nykjær, A., Gliemann, J., Kasper, D., Pohlmann, R.
& Pedersen, J. C. M. (2001).
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.
EMBO Journal,
20, 2180-2190.
Jensen, P. H., Islam, K., Kenney, J.
, Nielsen, M. S., Power, J. & Gai, W. P. (2000).
Microtubule-associated protein 1B is a component of cortical lewy bodies.
Journal of Biological Chemistry,
275, 21500-21507.
Chan, W. L., Shaw, P. C., Tam, S. C.
, Jacobsen, C., Gliemann, J. & Nielsen, M. S. (2000).
Trichosanthin interacts with and enters cells via LDL receptor family members.
Biochem. Biophys. Res. Commun.,
270, 453-457.
Jensen, P. H., Hager, H.
, Nielsen, M. S., Højrup, P.
, Gliemann, J. & Jakes, R. (1999).
Alpha-synuclein binds TAU and stimulates the protein kinase A-catalyzed TAU phosphorylation of serine residues 261 and 356.
Journal of Biological Chemistry,
274, 25481-25489.
Petersen, C. M., Nielsen, M. S., Jacobsen, C., Tauris, J., Jacobsen, L.
, Gliemann, J., Moestrup, S. K. & Madsen, P. S. (1999).
Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.
EMBO Journal,
18, 595-604.
Nielsen, M. S., Jacobsen, C., Olivecrona, G.
, Gliemann, J. & Petersen, C. M. (1999).
Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase.
Journal of Biological Chemistry,
274, 8832-8836.
Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, C. G. & Goedert, M. (1998).
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
J Biol Chem Commun,
273, 26292-26294.
Tauris, J., Ellgaard, L.
, Jacobsen, C., Nielsen, M. S., Madsen, P. S., Thøgersen, H. C., Gliemann, J., Petersen, C. M. & Moestrup, S. K. (1998).
The carboxy-terminal domain of the receptor-associated protein binds to the Vps10p domain of sortilin.
FEBS Letters,
429(1), 27-30.
Jensen, P. H., Højrup, P., Hager, H.
, Nielsen, M. S., Jacobsen, L., Olesen, O. F.
, Gliemann, J. & Jakes, R. (1997).
Binding of Aβ to α- and β-synucleins: Identification of segments in α-synuclein/NAC precursor that bind Aβ and NAC.
Biochemical Journal,
323, 539-546.
Hager, H.
, Jensen, P. H., Hamilton-Dutoit, S. J., Nielsen, M. S., Birckbichler, P.
& Gliemann, J. (1997).
Expression of tissue transglutaminase in human bladder carcinoma.
J Pathol,
183, 398-403.
Petersen, C. M., Nielsen, M. S., Nykjær, A., Jacobsen, L., Tommerup, N., Rasmussen, H., Røigaard, H.
, Gliemann, J., Madsen, P. S. & Moestrup, S. K. (1997).
Molecular identification of anovel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography.
Journal of Biological Chemistry,
272, 3599-3605.
Nielsen, M. S., Brejning, J., García, R., Zhang, H., Hayden, M. R., Vilaró, S.
& Gliemann, J. (1997).
Segments in the C-terminal folding domain of lipoprotein lipase important for binding to the low density lipoprotein receptor-related protein and to heparan sulfate proteoglycans.
Journal of Biological Chemistry,
272(9), 5821-5827.
http://www.jbc.org/cgi/content/full/272/9/5821
Leffers, H., Dejgaard, K.
, Honore, B., Madsen, P. S., Nielsen, M. S. & Celis, J. (1996).
cDNA expression and human two-dimentional gel protein databases: Towards integrating DNA and protein information.
Electrophoresis,
17, 1713-1719.
Krapp, A., Ahle, S., Kersting Hua, Y., Kneser, K.
, Nielsen, M. S., Gliemann, J. & Beisiegel, U. (1996).
Hepatic lipase mediates the uptake of chylomicrons and β-VLDL into cells via the LDL receptor-related protein (LRP).
J. Lipid Res.,
37, 926-936.
Petersen, C. M., Ellgaard, L.
, Nykjær, A., Vilhardt, F.
, Vorum, H., Thøgersen, H. C., Nielsen, M. S., Jacobsen, C., Moestrup, S. K. & Gliemann, J. (1996).
The receptor-associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin-dependent kinase II.
EMBO Journal,
15(16), 4165-4173.
