Petersen, C. M., Nielsen, M. S., Nykjær, A., Jacobsen, L., Tommerup, N., Rasmussen, H., Røigaard, H.
, Gliemann, J., Madsen, P. S. & Moestrup, S. K. (1997).
Molecular identification of anovel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography.
Journal of Biological Chemistry,
272, 3599-3605.
Hudecz, D., McCloskey, M. C., Vergo, S., Christensen, S., McGrath, J. L.
& Nielsen, M. S. (2023).
Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device.
International Journal of Molecular Sciences ,
24(6), Article 5624.
https://doi.org/10.3390/ijms24065624
Jensen, P. H., Islam, K., Kenney, J.
, Nielsen, M. S., Power, J. & Gai, W. P. (2000).
Microtubule-associated protein 1B is a component of cortical lewy bodies.
Journal of Biological Chemistry,
275, 21500-21507.
Amoushahi, M., Steffensen, L. L., Galieva, A., Agger, J., Heuck, A., Siupka, P., Ernst, E., Nielsen, M. S., Sunde, L. & Lykke-Hartmann, K. (2020).
Maternally contributed Nlrp9b expressed in human and mouse ovarian follicles contributes to early murine preimplantation development.
Journal of Assisted Reproduction and Genetics,
37(6), 1355-1365.
https://doi.org/10.1007/s10815-020-01767-w
Strandgaard, T., Foder, S., Heuck, A., Ernst, E., Nielsen, M. S. & Lykke-Hartmann, K. (2017).
Maternally Contributed Folate Receptor 1 Is Expressed in Ovarian Follicles and Contributes to Preimplantation Development.
Frontiers in Cell and Developmental Biology,
5(SEP), Article 89.
https://doi.org/10.3389/fcell.2017.00089
Matrone, C., Dzamko, N.
, Madsen, P., Nyegaard, M., Pohlmann, R., Søndergaard, R. V.
, Lassen, L. B., Andresen, T. L., Halliday, G. M.
, Jensen, P. H. & Nielsen, M. S. (2016).
Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.
PLOS ONE,
11(8), e0160501. Article e0160501.
https://doi.org/10.1371/journal.pone.0160501
Nielsen, S. S. E., Siupka, P., Georgian, A., Preston, J. E.
, Tóth, A. E., Yusof, S. R., Abbott, N. J.
& Nielsen, M. S. (2017).
Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells.
Journal of Visualized Experiments,
2017(127), Article e56277.
https://doi.org/10.3791/56277
Leffers, H.
, Nielsen, M. S., Andersen, A. H.
, Honore, B., Madsen, P. S., Vandekerckhove, J. & Celis, J. (1993).
Identification of two human Rho GDP-dissociation inhibitor protein whose overexpression leads to disruption of the acting cytoskeleton.
Exp. Cell Res.,
209, 165-174.
Madsen, P., Isaksen, T. J., Siupka, P., Tóth, A. E., Nyegaard, M., Gustafsen, C. & Nielsen, M. S. (2019).
HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA.
Scientific Reports,
9, Article 611.
https://doi.org/10.1038/s41598-018-37336-6
Krapp, A., Ahle, S., Kersting Hua, Y., Kneser, K.
, Nielsen, M. S., Gliemann, J. & Beisiegel, U. (1996).
Hepatic lipase mediates the uptake of chylomicrons and β-VLDL into cells via the LDL receptor-related protein (LRP).
J. Lipid Res.,
37, 926-936.
Westergaard, U. B.
, Sørensen, E. S., Hermey, G.
, Nielsen, M. S., Nykjær, A., Kirkegaard, K., Jacobsen, C., Gliemann, J., Madsen, P. S. & Pedersen, J. C. M. (2004).
Functional organization of the sortilin Vps10p domain.
Journal of Biological Chemistry,
279, 50221-50229.
Hager, H.
, Jensen, P. H., Hamilton-Dutoit, S. J., Nielsen, M. S., Birckbichler, P.
& Gliemann, J. (1997).
Expression of tissue transglutaminase in human bladder carcinoma.
J Pathol,
183, 398-403.
Burkhart, A., Skjørringe, T., Johnsen, K. B.
, Siupka, P., Thomsen, L. B.
, Nielsen, M. S., Thomsen, L. L. & Moos, T. (2015).
Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier.
Molecular Neurobiology.
https://doi.org/10.1007/s12035-015-9582-7
Nilsson, S. K.
, Christensen, S., Raarup, M. K., Ryan, R. O.
, Nielsen, M. S. & Olivecrona, G. (2008).
Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.
Journal of Biological Chemistry,
283(38), 25920-7.
https://doi.org/10.1074/jbc.M802721200
Progida, C.
, Nielsen, M. S., Koster, G., Bucci, C. & Bakke, O. (2012).
Dynamics of Rab7b-dependent transport of sorting receptors.
Traffic,
13(9), 1273–1285.
https://doi.org/10.1111/j.1600-0854.2012.01388.x
Sarret, P., Krzykowski, P., Segal, L.
, Nielsen, M. S., Pedersen, J. C. M., Mazella, J., Stroh, T. & Beaudet, A. (2003).
Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system.
J. Comp. Neurol., (461), 483-505.
Larsen, J. V., Kristensen, A. M., Pallesen, L. T., Bauer, J., Vægter, C. B., Nielsen, M. S., Madsen, P. & Petersen, C. M. (2016).
Cytokine-like factor-1 (CLF-1): An essential facilitator of cardiotrophin-like cytokine: CNTFRα (CLC:CNTFRα) signalling and sorLA mediated turnover.
Molecular and Cellular Biology.
https://doi.org/10.1128/mcb.00917-15
Yan, Y., Gu, T., Christensen, S. D. K., Su, J., Lassen, T. R., Hjortbak, M. V., Lo, I., Venø, S. T., Tóth, A. E., Song, P., Nielsen, M. S., Bøtker, H. E., Blagoev, B.
, Drasbek, K. R. & Kjems, J. (2021).
Cyclic hypoxia conditioning alters the content of myoblast-derived extracellular vesicles and enhances their cell-protective functions.
Biomedicines,
9(9), Article 1211.
https://doi.org/10.3390/biomedicines9091211
Nykjær, A., Fyfe, J. C., Kozyraki, R., Leheste, J. R.
, Jacobsen, C., Nielsen, M. S., Verroust, P. J., Aminoff, M., de la Chapelle, A.
, Moestrup, S. K., Ray, R.
, Gliemann, J., Willnow, T. E.
& Christensen, E. I. (2001).
Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).
Proceedings of the National Academy of Sciences,
98, 13895-13900.
Kristensen, M., Kucharz, K., Felipe Alves Fernandes, E., Strømgaard, K.
, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, A., Ulrikkaholm Tofte-Hansen, M., Irene Aldana Garcia, B., Lauritzen, M. & Brodin, B. (2020).
Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation.
Pharmaceutics,
12(7), 1-24. Article 661.
https://doi.org/10.3390/pharmaceutics12070661
Christensen, S. C., Krogh, B. O., Jensen, A.
, Andersen, C. B. F., Christensen, S.
& Nielsen, M. S. (2020).
Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain.
Scientific Reports,
10(1), Article 14582.
https://doi.org/10.1038/s41598-020-71286-2
Ozgür, B., Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V.
, Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, M., Auriola, S., Jensen, A., Fricker, G.
, Nielsen, M. S., Neuhaus, W. & Brodin, B. (2023).
Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line.
Fluids and Barriers of the CNS,
20(1), Article 96.
https://doi.org/10.1186/s12987-023-00501-9
Leffers, H., Dejgaard, K.
, Honore, B., Madsen, P. S., Nielsen, M. S. & Celis, J. (1996).
cDNA expression and human two-dimentional gel protein databases: Towards integrating DNA and protein information.
Electrophoresis,
17, 1713-1719.
Kahns, S., Lykkebo, S., Jakobsen, L. D.
, Nielsen, M. S. & Jensen, P. H. (2002).
Caspase-mediated parkin cleavage in apoptotic cell death.
Journal of Biological Chemistry,
277, 15303-15308.
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, J.
, Glerup, S. & Nielsen, M. S. (2018).
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner.
Behavioural Brain Research,
348, 90-100.
https://doi.org/10.1016/j.bbr.2018.04.017
Jensen, P. H., Højrup, P., Hager, H.
, Nielsen, M. S., Jacobsen, L., Olesen, O. F.
, Gliemann, J. & Jakes, R. (1997).
Binding of Aβ to α- and β-synucleins: Identification of segments in α-synuclein/NAC precursor that bind Aβ and NAC.
Biochem. J.,
323, 539-546.
Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, C. G. & Goedert, M. (1998).
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
J Biol Chem Commun,
273, 26292-26294.
Siupka, P., Hersom, M. N.
, Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B.
& Nielsen, M. S. (2017).
Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.
Journal of Cerebral Blood Flow and Metabolism,
37(7), 2598-2613. Article 271678X17700665.
https://doi.org/10.1177/0271678X17700665
Christensen, S. C., Hudecz, D., Jensen, A., Christensen, S.
& Nielsen, M. S. (2021).
Basigin Antibodies with Capacity for Drug Delivery Across Brain Endothelial Cells.
Molecular Neurobiology,
58(9), 4392-4403.
https://doi.org/10.1007/s12035-021-02421-x
Nielsen, S. S. E., Holst, M. R., Langthaler, K., Christensen, S. C.
, Bruun, E. H., Brodin, B.
& Nielsen, M. S. (2023).
Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells.
Fluids and Barriers of the CNS,
20(1), Article 2.
https://doi.org/10.1186/s12987-022-00404-1
Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S.
, Nielsen, M. S., Moos, T. & Andresen, T. L. (2018).
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.
Theranostics,
8(12), 3416-3436.
https://doi.org/10.7150/thno.25228
Nyegaard, M., Rendtorff, N. D.
, Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., Hedemand, A., Buniello, A., Niola, F., Overgaard, M. T., Leal, S. M., Ahmad, W.
, Wikman, F. P., Petersen, K. B., Crüger, D. G., Oostrik, J., Kremer, H., Tommerup, N., Frödin, M.
... Børglum, A. D. (2015).
A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.
P L o S Genetics,
11(7), e1005386.
https://doi.org/10.1371/journal.pgen.1005386
Horn, I. R.
, Moestrup, S. K., van den Berg, B. M. M., Pannekoek, H.
, Nielsen, M. S. & van Zonneveld, A. J. (1995).
Analysis of the binding of pro-urokinase-plasminogen activator inhibitor-1 complex to the low density lipoprotein receptor-related protein using a Fab fragment selected from a phage-displayed Fab library.
Journal of Biological Chemistry,
270, 11770-11775.
Nielsen, M. S., Nykjær, A., Warshawsky, I., Schwartz, A. L.
& Gliemann, J. (1995).
Analysis of ligand binding to the α2-macroglobulin receptor/low density lipoprotein receptor-related protein.
Journal of Biological Chemistry,
270, 23713-23719.
Jensen, P. H., Hager, H.
, Nielsen, M. S., Højrup, P.
, Gliemann, J. & Jakes, R. (1999).
Alpha-synuclein binds TAU and stimulates the protein kinase A-catalyzed TAU phosphorylation of serine residues 261 and 356.
Journal of Biological Chemistry,
274, 25481-25489.